The key enantioselectivity determining step in the synthesis is given below. Provide a mechanism. Br Ts 20 mol% CO₂H 5 mol % Pd(OAC)2 15 mol% PPh3

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter8: Haloalkanes, Halogenation, And Radical Reactions
Section: Chapter Questions
Problem 8.24P
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The key enantioselectivity determining step in the synthesis is given below. Provide a
mechanism.
Br
Ts
20 mol%
CO₂H
5 mol % Pd(OAc)2
15 mol% PPh3
Ts
Transcribed Image Text:The key enantioselectivity determining step in the synthesis is given below. Provide a mechanism. Br Ts 20 mol% CO₂H 5 mol % Pd(OAc)2 15 mol% PPh3 Ts
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