The Lineweaver-Burk plots in this figure represent the activities of enzymes in the absence and presence of different types of inhibitors. Which one represents the activity of the enzyme in the presence and absence of a mixed inhibitor? (choose the one best answer).
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- 22:23 1O 000 · 11:24 A9 OB1 r ll l 52% . +964 782 734 3923 2m541139927815107... Patient Encounter Part 3 The pretreatment workup is summarized below. Pathology: 47-year-old female with new diagnosis of infiltrating intraductal adenocarcinoma involving the left breast and regional node. Further tests on tumor samples indicated ER (8%), PR (negative), HER2 (negative), Ki-67 (72%), and grade (poorly differentiated). Intrinsic subtype (luminal B, HER2-negative). Radiology: FDG-PET/CT indicated a 5.3 x 2.5 cm mass in the left breast which appeared to extend to the epidermis of the skin; one node in the left axilla was also involved with tumor. No other evidence of distant disease was visualized. Laboratory: CBC, liver, and kidney function tests WNL, alkaline phosphatase and calcium are normal also. Stage: IB (T, N, M,) List the most important prognostic factors in this patient with newly diagnosed breast cancer. Assess the patient's level of risk for relapse. 50 SECTION 16 | ONCOLOGIC…Based on the image below, select the correct statement. Complex II QH₂ Q- 10 2 HO 2 HO Fe-S (2.8 FADH₂ FAD- Succinate Fumarate https://canvas.uts.edu.au/assessment questions/356986/files/1562694/download? 2e verifier-eUTT3hYal2YYTWlywV8TIFA3USmzCsM52jECmvTo O Succinate is reduced to fumarate O Succinate is oxidised to FAD O The Fe-S center shuffles electrons from FAD to ubiquinone (Q) O The Fe-S center shuffles electrons from FADH2 to ubiquinone (Q) The Fe-S center shuffles electrons from FADH2 to ubiquinonol (QH2) W 88 16°C1. Compute for the following:- D5LR 1 L to run for 8 hours. How many drops/min. (drop factor= 15gtts/cc)- Order: Mg So4 20% 2g. slow iv push “stat” (Stock dose= 20% at 10g./50 ml) How many ml should be given? 2. Questions: What is the indication for Mg So4 in this patient? How should it be administered intravenously? What is/are the adverse effects of this drug on the mother/fetus which need to be watched out for? Thank you! :)
- 1. https://doi.org/10.1186/s12868-022-00692-1 (link to research) a) In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “Post-administration of mitoxantrone to sedentary and exercised groups smaller patches of demyelination with microcyst formation and lymphocytic infiltrates were seen; and bare unmyelinated axons were fewer (Figs. 3D, E, I, J and 4D, E, I, J).” Based on this quote, what is mitoxantrone doing exactly/directly? b) In the histopathological study section of the materials and methods section the authors wrote “Luxol fast blue (LFB) staining was used for assessment of demyelination in the cerebellum and brain stem and scored as described previously by Zhang et al. [21] and illustrated in Table 2.” Why was demyelination assessed in this study?Rh-hr Kell Duffy Xg Results D C E с Kp Kp Js Js Fy Fy Xg AHG 0.2 M DTT + + + 0 + + 2+ 2+ + 0 0 0 0 + 0 + 0 0 0 0 + Neg Neg 0 0 + 0 + + 0 + 0 0 + +2+ Neg +2+ 2+ + + + + 0 + 0 + 0 0 + + 0 + + 0 + 0 + 0 + 0 +2+ 24 + 0 0 0 0 + 0 + 0 0 + + 0 Neg Neg ID4 0 + + 0 0 0 + 0 + 0 + +2+ 2+ Neg Neg ID5 0 0 + 0 0 + 0 + + 0 + 0 + + ID6 0 0 + 0 + + 0 0 0 0 + + + 0 + 0 2+ Neg ID7 0 0 + 0 0 + 0 0 0 + 0 0 0 0 + 0 0 + + Neg Neg ID8 + 0 + + 0 0 + 0 + 0 0 + 0 0 + 0 + + 0 + + Neg Neg ID9 0 0 + 0 0 0 + 0 0 + + 0 0 0 + 0 + + + 0 Neg Neg ID10 000 + 0 0 + + + 0 0 0 + 0 + + 0 + 0 + 0 Neg Neg ID11 000 + 00+ 0+ 0 0 + 0 + 0 + 0 + 0 0 + +Neg Neg AC Neg AC, auto control; SC, screening cells; ID, identification panel; Neg. Negative reaction Note: SC1 to SC3 are screening cells, ID1 to ID11 are panel cells. All screening and panel cells have negative results with the IS phase and Thermo Phase. 1. What is the result of the Antibody Screening test? 2. Which of the following panel cells contain only the Js" antigen? 3.…E Share O Comm Cambria 12 v A A Aa v - v AaBbCcDdEe AaBbCcDdE AaBbCcDdEe BIUV ab X. A v 2v A v List Paragraph Normal No Spacing Styles Pane Dictate Sensitivit 4. Explain two different ways that the body can respond to low blood oxygen content. Describe the entire feedback loop, including where problem is sensed, what signals are sent by the sensing organ, and how the eventual changes in the body change the oxygen content of the blood. 241% Focus Page 2 of 3 English (United States) 372 words
- in Course: 23SPCMP Anat & Phys... The tissue type that is indicated by the black line is @ # M Question 32 - Lab Practical 1 -... $ % LM 320x 4+5) When the number of spare receptor is much more than the amount of irreversible antagonist X, what will happen to the agonist Y when it is co-administrated with X? a. There will be a downward shift of log dose response curve b. There will be a upward shift of log dose response curve c. There will be a right shift of log dose response curve d. There will be a left shift of log dose response curve e. There will be no change for log dose response curve 6) The maximum plasma concentration of a drug is reached when a. The elimination rate equals the absorption rate b. The elimination rate is very high c. The elimination rate is lower than the absorption rate d. The elimination rate is minimum e. The absorption far exceeds the elimination rate 7) Most drug receptors a a. Carbohydrate b. Phospholipids c. Steroids d. Proteins e. Enzymes5) When the number of spare receptor is much more than the amount of irreversible antagonist X, what will happen to the agonist Y when it is co-administrated with X? a. There will be a downward shift of log dose response curve b. There will be a upward shift of log dose response curve c. There will be a right shift of log dose response curve d. There will be a left shift of log dose response curve e. There will be no change for log dose response curve
- Flonase NS #1 ii sprays in each nostril QD. How many days will the medication last?A patlent has been prescribed 1.25 mg ramipril capsules 43h poat myocardial infarction. How many capaules need to be dapenned for a 14 dey supely Assume that ramipril is wel tolerated 1. Name of the medicinal product Ramipril 1.25 mg capsules, hard 2. Qualitative and quantitative composition Ramipril 1.25 mg, capsules, hard contains 1.25 mg of ramipril For the full list of excipients, see section 6.1. Symptomatic heart failure Starting Dose: In patients stabilized on diuretic therapy, the recommended initial dose is 1.25 mg daly. Titration and maintenance dose Ramipril should be titrated by doubling the dose every one to two weeks up to a maximum daily dose of 10 mg. Two administrations per day are preferable. Secondary prevention after acute myocardial infarction and heart failure Starting Dose After 48 hours, following myocardial infarction in a clinically and haemo dynamically stable patient, the starting dose is 2.5 mg twice daily for three days. If the initial 2.5 mg dose is not…A physician order s Sentamycin 40mg lvqah fur a'child who The recommended do3age fur childrenis 3 - bmgl ) weighs 24 1bs. Kgl day In three divided doses . a what recummended minimum E maseimum daily dosages are the for this child ? b) what are the cmmended minimum single recor dosages fur this child? c) Is the ordered dosage safe ?
