The mechanism of acquired drug resistance that would prohibit the drug molecule from entering a target cell would be considered: Use of alternate metabolic pathway Drug inactivation Activation of drug pumps Decreased permeability Change in drug binding site
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- Apart from simple diffusion, suggest TWO ways how do drugs pass through the cell membrane and the properties of the drugs that is suitable for that way.Identify the classification of drug metabolism and specific type of reaction involved in each drugsample. Identify the enzyme involved in each reaction.In what cellular process does the drug target play a role?
- Biotransformation is an important concept in pharmacology, which amongst others, enables the effective administration of prodrugs. Provide a detailed description of factors influencing the biotransformation of drugs.In your own understanding, which among the routes/forms of drug administration above has the most rapid absorption? Has the slowest absorption? Explain your answer.How does physicochemical properties of a drug define its biological mechanism? Please explain at your own words.
- Antiparkinson agent Format as follows. - side effects of the drug -contraindications -List 3 examples - client educationDescribe the enzymatic reaction of the protein epidermal growth factor. Include the specific reaction catalyzed by the protein. Enzymatic reaction is a physiologically relevant biochemical stimulus for the temporal and spatial control of drug release because: (1) the overexpression of specific enzymes is localized at diseased tissues.List and explain in your own words the 5 mechanisms of antimicrobial drug resistance