The membrane of the mammary gland separates blood (pH = 7.4) from milk (pH = 6.6). You are given the following drug information about drug A: weak base, pK =10. What is Brodie’s D value (total drug concentration in milk/ total drug concentration in blood plasma) for the transport of drug A from blood plasma to milk? A. 0.16 B. 1.6 C. 6.3 D. 16 E. 63

The membrane of the mammary gland separates blood (pH = 7.4) from milk (pH = 6.6). You are given the following drug information about drug A: weak base, pK =10. What is Brodie’s D value (total drug concentration in milk/ total drug concentration in blood plasma) for the transport of drug A from blood plasma to milk? A. 0.16 B. 1.6 C. 6.3 D. 16 E. 63

Chemistry: The Molecular Science

5th Edition

ISBN:9781285199047

Author:John W. Moore, Conrad L. Stanitski

Publisher:John W. Moore, Conrad L. Stanitski

Chapter14: Acids And Bases

Section14.5: Ionization Constants Of Acids And Bases

Problem 14.11CE

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