Case Study Four Case Study Assessing Dose Accuracy and Safety and Label Clarity The Pharmacy Department of Miracle Hospital has ordered premixed solutions of cyclophosphamide 200 mg per 500 mL of NaCl 0.9%w/v injection from a specialty pharmacy compounding various parenteral products. The commercial 500 mL NS solution PVC bag has an overfill. The specialty pharmacy prepared the cyclophosphamide admixture by adding 10 mL of a reconstituted solution of 20 mg/mL cyclophosphamide to the 500 mL of NaCl 0.9%w/v PVC bag and labelled the IV admixture as 200 mg of cyclophosphamide per 500 mL. What is the concentration per millilitre of the cyclophosphamide admixture? (Napra 3.1) What volume of this admixture would you draw-up in a syringe to deliver a 40 mg dose? (Napra 3.1) What potential error could result if the premixed cytotoxic admixture is used? (Napra 6.1, 6.2, 9.2)
Case Study Four
Case Study Assessing Dose Accuracy and Safety and Label Clarity
The Pharmacy Department of Miracle Hospital has ordered premixed solutions of cyclophosphamide 200 mg per 500 mL of NaCl 0.9%w/v injection from a specialty pharmacy compounding various parenteral products. The commercial 500 mL NS solution PVC bag has an overfill.
The specialty pharmacy prepared the cyclophosphamide admixture by adding 10 mL of a reconstituted solution of 20 mg/mL cyclophosphamide to the 500 mL of NaCl 0.9%w/v PVC bag and labelled the IV admixture as 200 mg of cyclophosphamide per 500 mL.
- What is the concentration per millilitre of the cyclophosphamide admixture? (Napra 3.1)
- What volume of this admixture would you draw-up in a syringe to deliver a 40 mg dose? (Napra 3.1)
- What potential error could result if the premixed cytotoxic admixture is used? (Napra 6.1, 6.2, 9.2)
Case Study Having Knowledge of the Clinical Use of Specialty Parenteral Solutions
Mark is a licensed pharmacy technician working in a hospital that provides dialysis to 20 patients with kidney failure. Some of these patients undergo hemodialysis, and some undergo peritoneal dialysis. All patients are treated at home.
Mark is responsible for managing the supplies for these patients, and his duties include providing prefilled syringes with sodium chloride and heparin and incorporating certain additives in the dialysate solutions as prescribed by the renal physician.
- Differentiate between hemodialysis and peritoneal dialysis. (Napra 6.1, 6.2, 9.2)
- Describe the dialysate solutions used in both procedures. (Napra 6.1, 6.2, 9.2)
- What type of additives could Mark be adding to the dialysate solutions, and why? (Napra 3.2, 3.3, 6.1, 6.2)
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Case Study Having Knowledge of the Clinical Use of Specialty Parenteral Solutions
Mark is a licensed pharmacy technician working in a hospital that provides dialysis to 20 patients with kidney failure. Some of these patients undergo hemodialysis, and some undergo peritoneal dialysis. All patients are treated at home.
Mark is responsible for managing the supplies for these patients, and his duties include providing prefilled syringes with sodium chloride and heparin and incorporating certain additives in the dialysate solutions as prescribed by the renal physician.
- Differentiate between hemodialysis and peritoneal dialysis. (Napra 6.1, 6.2, 9.2)
- Describe the dialysate solutions used in both procedures. (Napra 6.1, 6.2, 9.2)
- What type of additives could Mark be adding to the dialysate solutions, and why? (Napra 3.2, 3.3, 6.1, 6.2)