The pKa values of a compound with two ionizable groups are pK1 = 4.10 and pK2 between 7 and 10. A biochemist has 10 mL of a 1.0 M solution of this compound at a pH of 8.00. She adds 10.0 mL of 1.00 M HCl, which changes the pH to 3.20. What is pK2?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter9: Parenteral Medication Labels And Dosage Calculation
Section: Chapter Questions
Problem 6.7P
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The pKa values of a compound with two ionizable groups are pK1 = 4.10 and pK2 between 7 and 10. A biochemist has 10 mL of a 1.0 M solution of this compound at a pH of 8.00. She adds 10.0 mL of 1.00 M HCl, which changes the pH to 3.20. What is pK2?

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