What happens in the patched-smoothened signaling system if the hedgehog is NOT present?  A. In the absence of hedgehog , the cell-surface transmembrane protein called "Patched" represses transcription by degrading the "Smoothened" protein located on the cytoplasmic vesicle B. Hedgehog binds to the smoothened factor which inhibits and represses transcription by activating mutations C. The absence of the hedgehog protein induces transcription by allowing the patched portion to be silenced causing the smoothened protein to activate D. There is no relevance of the hedgehog, since transcription will occur regardless due to the presence of the Gli protein which acts as a transcription promoting factor.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question

48. What happens in the patched-smoothened signaling system if the hedgehog is NOT present? 

A. In the absence of hedgehog , the cell-surface transmembrane protein called "Patched" represses transcription by degrading the "Smoothened" protein located on the cytoplasmic vesicle
B. Hedgehog binds to the smoothened factor which inhibits and represses transcription by activating mutations
C. The absence of the hedgehog protein induces transcription by allowing the patched portion to be silenced causing the smoothened protein to activate
D. There is no relevance of the hedgehog, since transcription will occur regardless due to the presence of the Gli protein which acts as a transcription promoting factor.
Expert Solution
steps

Step by step

Solved in 2 steps

Blurred answer
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Anatomy and Physiology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Anatomy & Physiology
Anatomy & Physiology
Anatomy and Physiology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Human Anatomy
Human Anatomy
Anatomy and Physiology
ISBN:
9780135168059
Author:
Marieb, Elaine Nicpon, Brady, Patricia, Mallatt, Jon
Publisher:
Pearson Education, Inc.,
Anatomy & Physiology: An Integrative Approach
Anatomy & Physiology: An Integrative Approach
Anatomy and Physiology
ISBN:
9780078024283
Author:
Michael McKinley Dr., Valerie O'Loughlin, Theresa Bidle
Publisher:
McGraw-Hill Education
Human Anatomy & Physiology (Marieb, Human Anatomy…
Human Anatomy & Physiology (Marieb, Human Anatomy…
Anatomy and Physiology
ISBN:
9780321927040
Author:
Elaine N. Marieb, Katja Hoehn
Publisher:
PEARSON