What is the purpose of alternative splicing a. Alternative spiicing allows a protein to be included by multiple genes b. Alternative spicing allows for mutations to accumulate that won't affect the expression of a gene c. Alternative splicing allows for multiple mRNAs to be produced to ensure that the single proteins the gene and codes will be translated. d.

What is the purpose of alternative splicing a. Alternative spiicing allows a protein to be included by multiple genes b. Alternative spicing allows for mutations to accumulate that won't affect the expression of a gene c. Alternative splicing allows for multiple mRNAs to be produced to ensure that the single proteins the gene and codes will be translated. d.

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Description: What is the purpose of alternative splicinga. Alternative spiicing allows a protein to be included by multiple genes b. Alternative spicing allows for mutations to accumulate that won't affect the expression of a genec. Alternative splicing allows fo

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter14: Gene Regulation

Section: Chapter Questions

Problem 8TYU: Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription...

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a. Use circles for activators and squares for repressors. Draw the shapes bound to each promoter region. b. Under the word gene write “ON” or “OFF” to indicate if the gene is transcribed or not under the different conditions.
a. How do bacteria increase the efficiency of gene expression? Is this possible in eukaryotes? b. A mutation in the promoter of Gene K disrupts an enzyme binding site and results in the loss of Gene K expression. Is this change in gene expression likely happening at the transcriptional or the translational level? Explain. c. Propose three different mutations to prevent initiation, elongation, and termination of bacterial transcription, respectively. Explain how/why each mutation would prevent its respective step. (Hint: mutations can be in genes that encode proteins or regulatory DNA sequences)
Through alternative splicing, eukaryotes (a) reinforce gene inactivation (b) prevent transcription of heterochromatin (c) produce related but different proteins in different tissues (d) amplify genes to meet the requirement of high levels of a gene product (e) bind transcription factors to enhancers to activate transcription
Alternative splicing a. increases the number of proteins made from one gene b. increases the number of primary transcripts made from one gene c. increases the number of exons d. increases the number of introns
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Consider the two-line model of a gene below: A ΟΥ Y If the promoter is found to the left of the transcription initiation site, where would you find the transcribed region? A +1
Differential RNA splicing may result in: a. A shift in the ratio of mRNA produced from two neighboring genes b. Inversion of exons in the mature mRNA c. Production of the same protein from two different genes d. Production of two different proteins with different properties from a single gene
How does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choice
e. You also study the expression of a different mutants for this gene. For each mutant answer the following: Does this mutation change the sequence of the protein produced? Why or why not? If it does change the sequence of protein be sure to write out the new sequence. If it does not change the protein sequence, what effect (if any) would you expect it to have on expression of the gene? 1 20 ORI 40 60 5'...TTCGAGCTCTCGTCGTCGAGATACGCGATGATATTACTGGTAATATGGGGATGCACTATC..3' 3' ...AAGCTCGAGAGCAGCAGCTCTATGCGCTACTATAATGACCATTATACCCCTACGTGATAG...5' promoter
a. Show (on the image) 3 steps that must be taken to produce a mature mRNA molecule from this pre- mRNAb. Place an arrow at the 5’ end of intron 2. (splice site). c. Why is a promoter not shown in this image?
The insertion of transposable elements into genes can alter the normal pattern of expression. In the following situations, describe the possible consequences on gene expression.a. A LINE inserts into an enhancer of a human gene. b. A transposable element contains a binding site for a transcriptional repressor and inserts adjacent to a promoter. c. An Alu element inserts into the 3′ splice (AG) site of an intron in a human gene. d. A Ds element that was inserted into the exon of a maize gene excises imperfectly and leaves three base pairs behind in the exon. e. Another excision by that same Ds element leaves two base pairs behind in the exon. f. A Ds element that was inserted into the middle of an intron excises imperfectly and leaves five base pairs behind in the intron.
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