Which of the following first messengers is a polypeptide? O acetylcholine adrenaline O insulin Oprogesterone O epinephrine
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- Identify the structure highlighted in green: Epinephrine receptor ACh receptor Norepinephrine receptorWhich of the following first messengers is hydrophobic and binds to a nuclear receptor protein inside cells? Oglucagon epinephrine O acetylcholine Oglucocorticoid insulinWhich of these neurotransmitters is an endocannabinoid? ts O glutamate O adenosine O serotonin all are endocannabinoids none are endocannabinoids
- Which of the following substances acts as a neurotransmitter? catechol O norepinephrine O dopamine more than one response is correctA 67-year old man has been treated for prostate cancer. He is receiving a drug that blocks testosterone from binding to its intracellular receptor. Which of the following has this mechanism of action: Tamoxifen Flutamide Leuprolide Fulvestrant Interleukin-2Steroid hormones are derivatives of: cholesterol O polypeptides O tryptophan O tyrosine
- Endocrine Ligand acting on intracellular receptor should be: O Hydrophilic O Hydrophobic O Amphipathic O Macromolecule What kinds of molecules may pass throughWhich of the following can be synthesized from phenylalanine? Epinephrine Melatonin y-amino butyric acid serotonin spermidineA patient has a tumour of the chromaffin cells in the adrenal medulla. Whilst awaiting surgery, he is treated with an antagonist which reduces the consequences of adrenal medulla overactivity by binding alpha adrenergic receptors irreversibly. Which one of the following drugs has he been treated with? Answers A - E A Clopidogrel B Lansoprazole C Aspirin Propranolol E Phenoxybenzamine
- Which of the following is false? Steroids do not require a G protein and second messenger. The average pH of blood is 7.4 Increased levels of AMP will cause an increase in enzyme activity A G protein links the first messenger with the second messenger.The rate limiting enzymes for norepinephrine is respectively. Aromatic catecholaminase; serotonin methylase tyrosine carboxylase; tryptophan carboxylase amino acid decarboxylase; tyrosine decarboxylase tyrosine hydroxylase; tryptophan hydroxylase and for 5-HT isWhich of the following is/are not stimulated by cAMP? Phosphofructokinase Epinephrine Muscle phosphorylase Protein kinase A Brain phosphorylase
