Which of the following is incorrect regarding Grignard reaction to produce benzoic acid? O When using separatory funnel, stopper must be removed when draining out the bottom layer, O in this experiment, glasswares must be thoroughly dry, because Grignard reagent will be deactivated even with a tiny amount of water. After putting Mg fillings, iodine crystal, and stirring bar in, the round bottom flask should be directly heated with medium to medium high power of the hot plate. O when acidifying the reaction mixture, 1 M H₂PO4 should be used, and then followed by a gravity filtration. in the first extractions, the bottom layer contains most final product, therefore the second extraction is needed for the bottom layer.
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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