Which of the following will decrease the level of uric acid in the body? O Decrease optimal concentration of xanthine oxidase inhibitor O Lower deaminase action O Higher purine phosphorylase activity
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- When the pathogen Salmonella typhimurium infects mammalian cells, the host cell protease caspase-1 is enabled to cleave and thereby activate signaling proteins that instigate the immune response. The targets of caspase-1 also include aldolase and enolase. What eff ect would this have on the infected cell and why might this be advantageous to the organism?Individuals with the disease alkaptonuria fail to produce the enzyme homogentisic acid ? in their liver. permease meriase oxidase tyrosinase hydroxylaseProvide a diagram of the EPH RECEPTOR B2 (EPHB2) structure. Give annotations of binding sites and enzyme active sites.
- Many patients with glucose 6- phosphatase deficiency have high serum levels of urate. Hyperuricemia can be induced in normal people by the ingestion of alcohol or by strenuous exercise. Propose a common mechanism that accounts for these findings.Dehydroascorbate is unstable at pH values greater than 6 anddecomposes to form tartrate and oxalate. Cells use GSH toreduce the loss of ascorbate. What is the reaction pathwayfor the regeneration of ascorbate?What is the effect of a defective a(1→ 4) phosphatase in Pompe's disease (GSD II)? O Accumulation of abnormal, unbranched glycogen, leading to heart or liver failure and short fife expectancy O Glycogen accumulation in heart, leading to heart failure, muscle weakness, short life expectancy O Absence of UDP-glucose conversion to glycogen, leading to lack of muscle glycogen, exercise intolerance Glycogen accumulation due to lack of glucose-6-phosphate conversion to glucose, leading to liver enlargement, hypoglycemia, short life expectancy O Lack of complete degradation of glycogen to glucose. leading to mild hypoglycemia, enlarged liver and muscle weakness Submit Request Answer
- The following reaction is catalyzed by this type of enzyme? Coo COO™ I HIC-H H-C-H COO™ succinate isomerase hydrolase O ligase transferase oxidoreductase succinate dehydrogenase FAD FADH2 H-C || C-H COO fumarateTwo of the bypass reactions of gluconeogenesis involve: phosphorylation of the metabolite using phosphate from Pi. ☐ phosphorylation of the metabolite using phosphate from ATP. dephosphorylation of the metabolite without using it to make ATP. phosphorylation of ADP using phosphate from the metabolite.Infants do not have the ability to metabolize ethanol and are assumed to lack the enzyme alcohol dehydrogenase? What kind of regulation is this?
- asap8. In patients with diabetes mellitus type I, the biochemical disorders result from changes in fucl metabolism. One of these signs is acidosis. Explain why such patients have a deviation of blood pH from the norm? For this me the Ocuics, name d) specify the hormone that accelerates this preeursor formation and provide appropriate charts, starting from the hormone binding to adipocyte and concluding with precursor formation, give an explanation to the charts.Discuss the toxic effects of the ammonium ion and excess bicarbonate ion. What is the effect of high concentrations of NH4+ in the bloodstream? What are the two reasons NH4+ is so toxic to the brain? Why can the urea cycle also be considered as a bicarbonate ion disposal mechanism? Why is that important?
