Which statement is most accurate regarding genetics and the development of chronic disease (cancer, cardiovascular disease, diabetes mellitus type 2, etc)?
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- You may have heard about the diet that is based on a persons blood type and claims to restore the bodys natural genetic rhythms and improve health. Research may one day reveal exactly which foods might best turn on and off specific genes to defend against specific chronic diseases. No doubt marketers will rush to fill grocery shelves with foods manufactured to match genetic profiles. Why do you think these genetic approaches to diet and health might be more or less appealing than eating patterns that include a variety of fruits, vegetables, whole grains, milk products, and meats?If a dominant disorder is described as being 80% penetrant, what would this mean? The amount of expression within individuals varies O The disorder is present in 20% of the individuals that have the dominant allele 20% of the individuals who have the dominant allele may have genes that mitigate (prevent) the disorder and therefore do not display symptoms O The trait is present in 80% of the total population.Thoko’s father suffered a heart attack recently. He is 48 years old, does not exercise, is overweight and smokes ~30 cigarettes a day. As a fund manager, his job is stressful and he works extremely long hours. It is recognized that many complex, multifactorial conditions have both, an environmental and a genetic component. Based on the information provided, draw up/create a 1 page “health plan” for him to “reduce the environmental risk” for coronary heart disease
- Twin studies are often used in the research of human behavioral traits. Although helpful, there are limitations to these studies. All of the following are limitations to twin studies EXCEPT: Traits are assumed to be simple Mendelian inheritance, discounting additive alleles and epistasis Dizygotic twins will often share more than 50% of their genes Monozygotic twins are often treated more similarity than dizygotic twins O Twins studies are a mechanism to understand the genetic and environmental components of a trait Twins reared apart are often adopted out to families of similar income, ethnicity, and religionGenetics affects many aspects of our lives. Identify three ways genetics affects your life or the life of a family member or friend. The effects can be regularly encountered or can be one time only or occasional. CAVE. A gene called Q has two alleles, QFand QG, that encode alternative forms of a red blood cell protein thatallows blood group typing. A different, independentlysegregating gene called R has two alleles, RC and RD,permitting a different kind of blood group typing. Arandom, representative population of football fanswas examined, and on the basis of their blood typing,the following distribution of genotypes was inferred(all genotypes were distributed equally betweenmales and females):QFQFRCRC 202QFQG RCRC 101QGQG RCRC 101QFQFRCRD 372QFQG RCRD 186QGQG RCRD 186QFQFRDRD 166QFQG RDRD 83QGQG RDRD 83This sample contains 1480 fans in total.a. Is the population at Hardy-Weinberg equilibriumwith respect to either or both of the Q andR genes?b. After one generation of random mating within thisgroup, what fraction of the next generation of football fans will be QFQF(independent of their Rgenotype)?c. After one generation of random mating, what fraction of the next generation of football fans will…
- Non-additive genetic factors make children less resemble their parents. true or false (reason in your own words) (plagiarized answer from any website will get down)Match the following : Genetic testing Genetic screening Genetic screening programs Genetic screening opportunities A test with high senstivity A test with high specificity predictive tests Pre- symptomatic tests Pre dispositional test involves testing individuals for the genetic change underlying a condition for which there is no evidence. can show that an individual is more likely than others to develop a specified condition. indicate the presence of a causative genotype but the onset of signs and symptoms is not certain. are offered as part of our public health service. do not include conditions that show incomplete penetrance. is performed cases where the onset of signs and symptoms is considered inevitable. involves testing individuals for the genetic change underlying a condition for which there is evidence. has a low false positive rate has a low false negative rateTwo of the loci identified in the 2019 study were not identified in prior GWAS studies focused on this trait in people of European or African ancestry, and those studies identified some loci not identified in this 2019 study of Hispanic/Latino people. Which of the following statements is the most likely explanation for these discrepancies? O Some of the genes impacting prolonged QRS risk are different in people of different ancestry groups O People of Hispanic/Latino ancestry have a higher overall risk of prolonged QRS The methodology employed in this study was flawed People of Hispanic/Latino ancestry have a lower overall risk of prolonged QRS
- Which of the following statements about Mendelian or complex disease is TRUE? O Mapping of quantitative trait loci does relies on genetic variations that directly contribute to the trait of interest. O Genetic methods for studying Mendelian phenotypes, such as crossing, is not useful for mapping quantitative trait loci. Genetic factors determine Mendelian traits, while environmental factors determine complex traits. O Both Mendelian and complex traits are associated with single gene locus. Genome-wide association studies rely on polymorphic markers that are in linkage disequilibrium with alleles that contribute to the trait of interest.During interaction between genes and environment, the phenotype O changes the genotype O is expressed as discontinuous variation is variable and undergoes continuous change throughout the life of the organism can be quantitatively subdivided into genotypic and environmental components O is stable once it has been expressed in the organismExplain why you agree or disagree with each of thefollowing statements:a. We should not worry much about exposure totoxic chemicals because almost any chemical, at alarge enough dosage, can cause some harm.b. We should not worry much about exposureto toxic chemicals because, through geneticadaptation, we can develop immunities to suchchemicals.c. We should not worry much about exposureto toxic chemicals because we can use geneticengineering to reduce our susceptibility to theireffects.d. We should not worry about exposure to a chemical such as bisphenol A (BPA) because it has notbeen absolutely proven scientifically that BPA haskilled anyone.