You react the following molecule with a strong bulky base (like KOtBu), and you know that the Cl atoms are all susceptible to elimination under these conditions. You also know that there are two competing mechanisms by which this reaction can occur: Mechanism 1: The double bond can form in several steps, the slowest of which is unimolecular. In this mechanism, the Cl atom leaves first, and the base removes a beta hydrogen in a subsequent step. Highlight in blue the Cl atom that would be eliminated quickest if the reaction went by this type of mechanism. Mechanism 2: The double bond can form in a concerted bimolecular step, removing the Cl atom and a beta hydrogen in the process. Highlight in red the Cl atom that would be eliminated quickest if the reaction went by this type of mechanism. If you would highlight the same Cl atom for both mechanisms, highlight it in green instead. Cl Cl CI G
Catalysis and Enzymatic Reactions
Catalysis is the kind of chemical reaction in which the rate (speed) of a reaction is enhanced by the catalyst which is not consumed during the process of reaction and afterward it is removed when the catalyst is not used to make up the impurity in the product. The enzymatic reaction is the reaction that is catalyzed via enzymes.
Lock And Key Model
The lock-and-key model is used to describe the catalytic enzyme activity, based on the interaction between enzyme and substrate. This model considers the lock as an enzyme and the key as a substrate to explain this model. The concept of how a unique distinct key only can have the access to open a particular lock resembles how the specific substrate can only fit into the particular active site of the enzyme. This is significant in understanding the intermolecular interaction between proteins and plays a vital role in drug interaction.
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