Diabetes Mellitus
Diabetes is the seventh leading cause of death listed in the United States. Diabetes is the leading cause of blindness. “In 1996 diabetes contributed to more than 162,000 deaths”(Lewis 1367).
“Diabetes mellitus is not a single disease but a group of disorders with glucose intolerance in common” (McCance 674). Diabetes mellitus is a metabolic disorder characterized by hyperglycemia (increased blood sugar) and results from defective insulin production, secretion, and utilization. There are many forms of diabetes. “Diabetes increases the risk of heart and blood vessel disease, amputation, infections, kidney damage, eye problems (including blindness), and nerve malfunction” (Husain). I will briefly define the
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According to McCance the diagnosis of diabetes is based on (1) more than one fasting plasma glucose level greater than 140mg/dl, (2) elevated plasma glucose levels in response to an oral glucose test, and random plasma glucose levels above 200mg/dl combined with classic symptoms of polydipsia, polyphagia, and polyuria (674).
The pancreas is located partially behind the stomach in the abdomen. The pancreas is a mixed gland composed of endocrine and exocrine gland cells. These cells are called acinar cells. Acinar cells, forming the bulk of the gland, produce an enzyme-rich juice that is ducted into the small intestine during food digestion.
Scattered among the acinar cells are approximately a million pancreatic islets (islets of Langerhans), minute cell clusters that produce pancreatic hormones. The islets contain two major populations of hormone-producing cells, the glucagen-synthesizing alpha cells and the more numerous insulin-producing beta cells. Insulin and glucagons are intimately but independently involved in the regulation of the blood glucose levels. Their effects are opposite: Insulin is a hypoglycemic hormone (lowers blood sugar), whereas glucagon is a hyperglycemic hormone (increases blood glucose.) Islet cells also synthesize other peptides in small amounts. These include somatostatin
When the blood glucose levels rise above the optimum, the pancreas detects this, and sends a metabolic signal for the pancreas to produce insulin in the beta cells. The beta cells are a part of a cluster of cells called the Islets of Langerhan. The hormone insulin is made here because the pancreas is a part of the endocrine system. (4) Insulin helps our cells convert glucose into energy, and it helps our bodies store extra glucose for use later. Insulin does this by turning the extra food into larger packages of glucose called glycogen. Glycogen is stored in the liver and muscles. When the body consumes food the pancreas will produce more insulin than normal as more is needed, and less insulin when it is not needed as much. (7)
Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.
The pancreas, located behind the stomach, is a long, thin organ about the length of the hand. It
Diabetes Type 2 1.Diabetes is considered a life style disease because it is not something you were born with it is something you bring upon yourself, stress, don't enough exercise, eating too much of the wrong foods, pregnancy or family history cause this particular disease. 2. Type 2 diabetes, or non-insulin-dependent diabetes, is the most common form of diabetes. It effects the respiratory system In Type 2 diabetes, either the body does not produce enough insulin or the cells neglect the insulin. Insulin is needed for the body to be able to use sugar.
Diabetes is the seventh leading cause of death listed in the United States. Diabetes is the leading cause of blindness. "In 1996 diabetes contributed to more than 162,000 deaths"(Lewis 1367).
Uncontrolled diabetes can affect nearly every organ of the body; of which, heart disease and kidney failure are most commonly impacted. Known as diabetes mellitus, a collective term for various blood abnormalities, the term diabetes refers to either a scarcity of insulin in the body or the body’s inability to accept insulin. Though the symptoms of diabetes are manageable, many are unaware as to having it. According to the CDC report “2011 Diabetes Fact Sheet,” approximately 6 million people in the United States have undiagnosed diabetes. Undetected, diabetes can become deadly. In a recent World Health Organization report “Diabetes Action Now: An Initiative of the World Health Organization and the International Diabetes Federation,” it
People often do not realize how deadly and complicated diabetes is. When first diagnosed with diabetes patients may often be confused by how their lifestyle will have to change. Some patients may not even know how serious the complications may be. This information is to help not only the people who are affected by diabetes but also to inform everyone on how to help prevent the onset of diabetes.
need for increased understanding of the economic, and societal seriousness of diabetes and its complications, and of the escalating costs to individuals, families, workplaces, society and governments.
Diabetes mellitus, commonly referred to as diabetes, is a disease that is commonly overlooked as not being as serious as it actually is. According to the national diabetes fact sheet, in 2007, 71,382 people died from diabetes and doctors ruled that diabetes was a contributing cause of the death of an additional 160,022 people. That is a total of 231,404 deaths in one year related to diabetes (American Diabetes Association, 2013). Diabetes is definitely a disease that many should research to learn just how serious it really is.
Diabetes remains the 7th leading cause of death in the United States. The cost of care for diabetics and new cases of diagnosed diabetes patient’s rise more and more each year. In 2010 234’051 death certificates were issued with the mention of diabetes as a contributing factor to the death. About 60% of lower limb amputations were performed. The cost of care for diabetics is now at an astronomical high of $176 billion dollars. A change a most be made to prevent all of this loss. (American Diabetes Association, 2014)
Nearly 16 million people in the United States have diabetes, the disease classified as a problem with insulin. The problem could be that your body does not make insulin, does not make enough, or it simply does not know how to use it properly. Diabetes is also known as "diabetes mellitus".
* Polyuria - excretion of very large quantities of urine. Urine output can range from 2.5 liters per day to 15 liters per day, compared to about 1.5 to 2.5 liters per day in other adults without the condition.
Diabetes is a chronic metabolic disorder that "occurs when the body is unable to produce or respond to insulin, a hormone that allows blood glucose to enter the cells of the body and generate the body's energy" (Ebony, 115). Diabetes is a disease that affects approximately 3% of the world' population. In American alone, 10.3 million people report having diabetes, while an estimated 10 million more individuals may have undiagnosed diabetes (Morwessel, 540). The gene for diabetes is located in the HLA region on chromosome 6, and the most probable organization of the responsible gene is on a 19-kb region of INS-IGF2, which affects HLA-DR4 IDDM susceptibility. Diabetes Mellitus, was first diagnosed in the year 1000 BC, by the
Diabetes is a chronic condition in which the body produces too little insulin (Type One Diabetes) or can’t use available insulin efficiently ( Type Two Diabetes). Insulin is a hormone vital to helping the body use digested food for growth and energy.
The pancreas is a digestive organ that lies below the stomach, it is mostly made up of exocrine and endocrine tissues. The exocrine parts form sacs known as Acini, which connect to ducts with empty into the first part of the intestine (The duodenum). Smaller parts of the exocrine glands are dispersed all throughout the pancreas which are known as islets of Langerhans (Anon, Unknown).