Diabetic Synthesis Essay

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

Diabetes, Diabetes Mellitus, is a chronic illness this means that it has no cure and the symptoms persist over a long period of time. This illness is a result of an imbalance of hormones, insulin, produced in the pancreas. Insulin plays an important role in how the body uses food. Insulin enables the cells in the bloodstream to absorb and use glucose for fuel. If the pancreas produces too little or no insulin or if the insulin doesn’t work properly the person may become diabetic. Therefore, diabetics are not able to properly convert food into fuels needed by the body to function, which can seriously lead to physical consequences.

Most patients who have diabetes for an extended amount of time may end up with diabetic neuropathy, which is damage caused to the nerves; it affects the peripheral nerves, autonomic nerves, and focal nerves. From the high blood sugar, it can destroy parts of the patient’s blood vessels, heart, and kidneys. If diabetes is not treated, it will almost always cause heart disease or kidney disease.

Why are nerves often damaged in patients with diabetes mellitus, and what are some of the

"Diabetes mellitus is not a single disease but a group of disorders with glucose intolerance in common" (McCance 674). Diabetes mellitus is a metabolic disorder characterized by hyperglycemia (increased blood sugar) and results from defective insulin production, secretion, and utilization. There are many forms of diabetes. "Diabetes increases the risk of heart and blood vessel disease, amputation, infections, kidney damage, eye problems (including blindness), and nerve malfunction" (Husain). I will

Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while

Diabetes is a disease that affects the body’s ability to produce or use insulin. It is a precursor to numerous other diseases, which can quickly deteriorate patient’s health if

Similarly, an increase in the levels of lipid peroxidation was observed in Aβ-induced rat hippocampal cells, confirming previous reports [17]. Enzymatic antioxidants such as SOD, catalase, and GPX act as the cellular antioxidant defense mechanism against free radicals. Since NADPH is required for the regeneration of catalase from its inactive form, catalase activity might be decreased in Aβ induced toxicity due to reduced NADPH levels. In this study, we have reported that Honokiol treatment significantly increased the enzymatic antioxidant activities in APP-CHO cells. In addition, non-enzymatic antioxidants like GSH also exhibited beneficial neuroprotective effects against oxidative stress. GSH is an endogenous nonenzymatic antioxidant that prevents damage to cellular components caused by ROS such as free radicals and peroxides. GSH is oxidized to glutathione disulfide (GSSG) by ROS, thereby causing a reduction in the level of GSH. GR reduces GSSG to GSH via NADPH, which in turn is released by glucose-6-phosphate dehydrogenase [18]. Honokiol treatment upregulated the activity of these antioxidants in APP-CHO cells. In addition to oxidative stress, a strong association between insulin resistance and the development of AD has been demonstrated. Several studies have reported that insulin resistance (IR), an underlying characteristic of type 2 diabetes, is an important risk factor for AD

Type 2 diabetes is associated with poor sensitivity to insulin. This had led some some researchers to suggest that Alzheimer’s disease may in fact be another type of diabetes (Trivedi, Bijal, 2012).

Diabetes should be studied due to the increased trend affecting larger numbers of people. According to the American Diabetes Association, the annual incidence of diabetes was estimated at 18,436 with type 1 diabetes, 5,089 with type 2 diabetes. The severity of this condition can be life- threatening. If not taken care of, diabetes will end in extreme illnesses, and potentially death. It is important to take care of your body and make sure you are getting the proper nutrition needed. As stated by the American Diabetes Association, long-term complications of diabetes include potential loss of vision, renal failure, foot ulcers, amputations, and Charcot joints; and autonomic neuropathy causing gastrointestinal, genitourinary, and cardiovascular symptoms and sexual dysfunction. Patients with diabetes have an increased incidence

Diabetes is defined as a disease that involves blood sugar levels, glucose, and insulin. These all come together and cause major problems in the body. When glucose levels are too high, the body needs insulin to turn the glucose into energy for the cells. In type one diabetes, the body does not create the insulin needed, so the body cannot turn the glucose into energy, which leads to extremely high glucose levels (Diabetes). Type two diabetes, and the most common type is the result of the body making but not using the insulin that it makes well (Diabetes). Without glucose, high amounts of insulin will remain in the blood. However, constantly having high glucose levels will also cause problems with the kidneys, eyes, and other important nerves (Diabetes). Many studies have been done that show how elevated levels of glucose share dementia related outcomes.

Diabetes is caused by the pancreas not producing enough insulin or the cells of the body that do not respond to the insulin that is produced and this results in hyperglycaemia and hypoglycaemia .

Diabetes is a metabolic disease involving elevated blood glucose levels over a prolonged period of time due to defects in insulin secretion, insulin action, or both. Diabetes is Greek for “siphon” because of the observation of frequent thirst and urination. There are two general disorders within the classification of “diabetes”; Diabetes Insipidus is

Diabetes mellitus is a deadly disease in many parts of the world. It is a disease condition that is usually characterized with an elevated blood glucose level. Researchers over the years have worked to determine the metabolic pathways of the disease. It is

Diabetes Mellitus is “a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. It is a disease which is caused by the insufficient insulin secretion or decrease in the peripheral effects of insulin. It is a serious problem in terms of morbidity and mortality. The hyperglycemia is associated with long term damage, dysfunction and failure of various organs especially the eyes, kidneys, nerves, heart and blood vessels. It’s associated with many complications which includes blindness of the eyes and amputations of the extremities. It is also associated with neuropathy, retinopathy, and cardiovascular diseases which lead to mortalities.