Fetal Alcohol Syndrome
Many studies have established that a developing organism is susceptible to exogenous and endogenous factors during certain stage of the organism’s development. The effects of ethyl alcohol or ethanol on the developing fetus, which manifest a variety of characteristic abnormalities, are collectively called Fetal alcohol Syndrome. Ethanol exposure to the fetus causes various malformation ranging from the cellular to the organismic levels with the eventual results frequently being different levels of mental retardation (3).
Chick embryo studies provide a relatively good model for defining the effects of ethanol at many organizational levels of neurogenesis, cell death, neuronal migration and differentiation,
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The consequences of ethanol are dependent on the time of administration and duration of treatment (3).
Animal models have displayed conclusively that alcohol can alter normal development of the central nervous system. Alcohol exposure during development has been shown to modify brain growth, neuronal number, myelination, neurotransmitter levels and receptor binding, synaptogenesis, and many other aspects of neuronal metabolism and morphology. There are indications of alcohol’s immediate or short term teratogenic effects, typically recounting deficits or delays in brain growth parameters, measured in the animals that were still in early stages of development (2).
Most infants identified with FAS are microcephalic, hyperactive, and mentally retarded by age four to ten. This persistence of brain dysfunction is what causes the highest human and economic toll (2).
Several studies have exhibited reductions in neuronal number in developing animals following alcohol exposure. However, neuronal death is a consequence of normal development. Some neuronal populations maintain a fifty percent reduction in the number before stabilizing in an adult configuration. The possibility exists that developmental alcohol exposure may in at least some circumstances, be accelerating the deaths of only those neurons that
The science behind FAS is quite simple; as it is known that alcohol has a damaging effect on the body, it has similar consequences on the fetus. Since the fetus is constantly developing, the alcohol causes more serious defects to the unborn child. Alcohol exposure to a fetus is known as a teratogen. “Teratogens are substances or conditions that disrupt typical development in offspring as a result of gestational exposure and cause birth defects.” (Wilson & Fraser, 1977). Although the exposure to alcohol causes problems in the fetus, studies have shown that it may not accurately be the alcohol in the mother’s system that causes these defects, rather the byproducts that form when the body metabolizes the alcohol. This can lead to a decrease in brain cells, abnormal location of neurons, and gross malformation to the brain. Since alcohol causes this central nervous system damage, it is classified as a neurobehavioral teratogen, which is a group of teratogens that cause brain damage and modify behaviors. (Riley & Vorhees, 1986). The CNS damage is the primary defect due to alcohol and it is quite common to have these damages without any physical abnormalities. The more alcohol that is consumed the more birth defects that will arise in the
Many recent studies are claiming that alcohol damages some parts of the brain more than others, targeting particular biochemical pathways vital to the development, function, migration, and survival of certain nerve cells. Further research is being done to help find ways that will block some of alcohol's harmful effects on the fetus. One study has identified specific effects on molecules that regulate development and others that participate in cell signaling (Christensen 3). The cell-adhesion
The pathophysiology of alcoholism begins after alcohol the ingestion of alcohol. It is absorbed and unaltered through the stomach and intestines. Next it is distributed throughout the body through the blood and absorbed by all tissues and fluids (Huether, 2012, p. 72). Furthermore, in the liver the alcohol blood content is metabolized into acetaldehyde by the enzymes process of alcohol dehydrogenase (ADH), the microsomal ethanol oxidizing system (MEOS), and catalase (Huether & McCance, 2012). Next, the metabolizing effects the central nervous system (CNS) and exhibits a depressant action. It is first expressed in the subcortical structures of the brain. This has an effect of disorientation of motor skills and intellect. With an increase in blood alcohol concentration, the medullary centers become depressed and as a result affects respiration (Huether & McCance, 2012). In addition, the effects of alcoholism encourage hepatic and gastric changes. The hepatic effect is caused by acetaldehyde, in which, induces inflammation, fatty deposits and enlargement of the liver (Huether & McCance, 2012).
“ We found that one high dose of alcohol caused significant loss of brain stem cells.” Says Dr. Brien. Loosing brain cells at an early age is a serious issue. Teens can lack social skills and develop social anxiety, as well as depression. The suicide rate in teens have gone up tremendously in the past few years, consuming alcohol in under aged teens is a huge factor. Under aged drinking has become an ongoing issue, parents need to sit down with their children and address the seriousness of drinking irresponsibly, because not only will it affect their bodies long term, but they also one day may subject their parents to having them bury their
This paper explores the effects of prenatal alcohol exposure on motor development. With this topic, came many questions. They are: Is every child effected the same amount, or does it depends on how much the mother drank and how much the fetus was exposed to?, Is there anything the mother can do to reverse the effects of exposure, or perhaps lessen the damage on the child?, Is there a safe amount of alcohol that can be consumed without harm?, And lastly, do the effects of prenatal alcohol exposure ever go away? Coles et al. (2015) and Lucas et al. (2016) suggest answers and evidence to these questions. This paper explains what happens when a fetus is exposed to alcohol, and how it
As a result of pregnant women drinking, there have been a profuse amount of children born with Fetal Alcohol Syndrome. Armstrong and Abel confirm that it wasn’t until 1973
“Fetal Alcohol Spectrum Disorder (FASD) is an umbrella term describing the range of effects that can occur in an individual whose mother drank alcohol during pregnancy. These effects may include physical, mental, behavioral, and/or learning disabilities with possible lifelong implications” (HHS, 2005). FASD refers to conditions such as: fetal alcohol syndrome including partial FAS, fetal alcohol effects (FAE), alcohol related neurodevelopment disorder, alcohol-related birth defects. The conditions that are involved with FASD can range from mild to severe and it is not likely that two people share the exact same symptoms.
Intaking alcohol can be very risky and harmful to the brain. During the teen years or in early adulthood the human brain undergoes a large amount of time of development that is very important. If alcohol is present, it only takes thirty seconds for it to effect the brain and thus it begins to decreases that important development (Shannon). "Alcohol can effect parts of the
Fetal Alcohol Syndrome (FAS) is a pattern of mental, physical, and behavioral defects that may develop in the unborn child when its mother drinks during pregnancy. These defects occur primarily during the first trimester when the teratogenic effects of the alcohol have the greatest effect on the developing organs. The symptoms associated with FAS have been observed for many centuries, but it was not until 1968 that Lemoine and his associates formally described these symptoms in the scientific literature, and again in 1973 when Jones and associates designated a specific pattern of altered growth and dysmorphogenesis as the Fetal Alcohol Syndrome (Rostand, p. 302). The set of abnormalities characterized by Jones
Considering the multitudes of things that could go wrong during a pregnancy, why would mothers consume alcohol despite the warnings of possible birth defects? Many are familiar with the "Just Say No" campaign spearheaded by Nancy Reagan in the 1980 's to prevent drug and alcohol use among teens. However, many turn a blind eye to the warnings of the surgeon general stating alcohol consumption during pregnancy can result in birth defects. When a pregnant woman consumes alcohol, she puts her fetus at risk from mild to severe physical, mental and cognitive disabilities. Fetal alcohol spectrum disorder (FASD) is the term that is used to describe an array of disorders that occurs as a consequence of women consuming alcohol during pregnancy. There are many types of FASD including fetal alcohol syndrome (FAS), partial fetal alcohol syndrome, alcohol-related birth defects(ARBD), alcohol-related neurodevelopment disorder(ARND), and neurobehavioral disorder associated with prenatal alcohol exposure. Although alcohol consumption during pregnancy is ill-advised, throughout the United States mothers continue to drink during pregnancy. Being FASD is the most preventable of developmental disabilities, I will examine the irreparable consequences of alcohol consumption during pregnancy and its behavioral, physical, cognitive and educational implications on the fetus and the family.
Every year, about 40,000 babies are born with symptoms of prenatal alcohol exposure (Lupton, 2003). This number will only continue to grow if the risk of drinking alcohol while pregnant is not brought to the people’s attention. When the mother takes a drink of alcohol, so does the fetus, which will cause physical and behavioral problems after birth. Fetal Alcohol Syndrome (FAS) is completely preventable and irreversible. FAS awareness and prevention is important; expectant mothers need to know the background information about the syndrome, some common symptoms, signs, and treatments, and the mental and physical abnormalities that will occur because of this lifelong syndrome.
Fetal Alcohol Syndrome (FAS) refers to a group of physical and mental birth defects resulting from a women’s drinking alcohol heavily or at crucial stages during pregnancy. Fetal Alcohol Syndrome was first named and treated in the late 1960's. This condition results from the toxic effect of alcohol and its chemical factors on the developing fetus. FAS is the leading cause of mental retardation occurring in 1 out of every 750 births. The frequency of FAS occurs about 1.9 times out of every 1000 births according to the latest figures, and minor effects can be seen in up to 20% of pregnancies per year. This number changes drastically for women who are clearly alcoholics. As high as 29 children out of every 1000 births will suffer from FAS
Fetal alcohol spectrum disorder (known as FASD), is a term which encompasses a wide variety of negative health consequences as a result of exposure to alcohol while in the womb (Williams, 2006). This exposure has the potential to cause severe, permanent brain damage leading to cognitive and behavioural deficiencies throughout childhood and adolescence (Brown et al., 2015). FASD only occurs within the general population of North America in approximately 9.1 out of every 1000 births (McLachlan et al., 2014). However, this condition is much more prevalent in individuals involved in various stages of the justice system, affecting between 10% and 23% (McLachlan et al., 2014). This paper aims to explain how FASD affects a juvenile’s brain
1308). Fetal alcohol syndrome is a condition which may exist in infants when their mothers have abused alcoholic beverages during the term of their pregnancy. Fetal alcohol syndrome generally results in physical, mental and emotional damage to the offspring. For example, such infants are almost always of a smaller size and weight than normal infants at birth, and are found to have a smaller overall brain size as well. It has been noted that these factors often lead to developmental delays, fine-motor problems, and a higher risk of academic problems once the child enters school (Streissguth, 1986, p. 23). Fetal alcohol syndrome has also been related to such malformations in infancy as mental retardation, cerebral palsy and hyperactivity. In terms of learning disability, it has been found that fetal alcohol syndrome often results in decreased attention span and other difficulties which may require special education needs when the child reaches school age (Abel & Sokol, 1986, p. 330). Studies with laboratory animals have also indicated that fetal alcohol syndrome may be responsible for the impairment of learning and memory functions in the hippocampus area of the brain (p. 330). It has been noted that many of the incidental problems in infants caused by fetal alcohol syndrome can be overcome with corrective surgery;
The fastest sperm has finally reached the outskirts of the awaiting egg, its sole purpose in life has been fulfilled as it fuses with the oocyte. Lots of divisions begin to occur, what was once a zygote becomes a blastocyst, which becomes the embryo, and the beginning formation of a baby has commenced. The difficult part is over now, right? This could not be further from the truth. The development of a human, from fertilization to birth, is a very complex and intricate process. It is through very specific processes that an embryo develops normally, without any sort of functional or structural irregularities. When harmful substances like alcohol interrupt these processes, the contaminated environment surrounding and