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Structural Differences

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The effects of marijuana have been examined in several studies that focused on long-term structural differences, cognitive impairments, prenatal risks and neural functioning deficits. Long-term structural abnormalities include reductions in the volume of the hippocampus, amygdala and nucleus accumbens, where these structures also exhibited changes in density and shape. Participants in several studies showed impairment in memory, learning, concentration, coordination, as well as decreased motivation. Marijuana has addictive properties and has dramatically increased in potency over the last decade, which has led to an increase in marijuana-related fatal car accidents and to an increase in emergency room visits. On the contrary, the non-psychoactive …show more content…

According to this article, animal literature had already confirmed that long-term marijuana use causes a decrease in neuronal volume of the hippocampus; however brain imaging studies of humans who were chronic users had less consistent results in the past. Researchers measured verbal learning ability, as well as psychotic symptoms to determine whether long-term marijuana use contributes to structural differences in two key brain regions. Structural MRI data was collected using a 3-T scanner, while participants also had to complete the Rey Auditory Verbal Learning Test. The results of the study had confirmed “gross anatomical abnormalities in 2 cannabinoid receptor-rich regions of the brain, the hippocampus and the amygdala” (Yucel, 2008). The hippocampus is typically associated with memory, although there may be also a connection between the left part of the hippocampus and psychiatric disorders with psychotic symptoms, which tend to occur more on the left hemisphere. Reduced activation of the left hippocampus in marijuana users found in brain imaging scans may not be directly related to the reduced volume of the hippocampus, however, it is clear that both lead to neurological abnormalities. This study had confirmed previous findings of decreased verbal performance, was found to be directly connected to the blood flow in the hippocampus and the amount of activation in that

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