Type 1 Diabetes Association (ADA)

Type 1 diabetes is caused by the pancreas not being able to produce insulin which regulates the levels of glucose in the blood (Bennett 17). People who struggle with this condition need insulin shots several times today to ensure their blood sugar remains in a healthy range. This often times is a burden on the diabetic's daily lifestyle. If unchecked, diabetes can cause severe weight loss, overwhelming tiredness, increased thirst and hunger, and excessive urination. Scientists and doctors have been seeking for ways to help diabetic's cope with this illness. After years of researching and testing, they have begun developing a method to help alleviate the problems of diabetes. This new method, islet cell transplantation,

Matthews, David. Diabetes. Oxford: Oxford University Press, 2008. eBook Collection (EBSCOhost). Web. 24 Oct. 2013.

Diabetes is a disease where the body is unable to produce or use insulin effectively. Insulin is needed for proper storage and use of carbohydrates. Without it, blood sugar levels can become too high or too low, resulting in a diabetic emergency. It affects about 7.8% of the population. The incidence of diabetes is known to increase with age. It’s the leading cause of end-stage renal disease in the US, and is the primary cause of blindness and foot and leg amputation. It is known to cause neuropathy in up to 70% of diabetic patients. Individuals with diabetes are twice as likely to develop cardiovascular disease. There are two types of diabetes: Type 1 and Type 2.

Type 1 diabetes is a disease that is most commonly diagnosed in children, is rarely diagnosed in adulthood, and “Diabetes at a glance” (2016) reveals that nearly two million people were newly diagnosed with the disease in 2016 in the U.S. alone, and one of the people included in that two million is myself. Throughout the

The American Diabetes Association (2004) defines diabetes as a subset of metabolic diseases associated with hyperglycemia secondary to insulin failing to release, act, or both. Complications related to chronic diabetes can be detrimental to one’s health including but not limited to: heart disease, stroke, kidney disease, amputations, blindness, and other optical diseases. Furthermore, the prevalence of diabetes is rising at an astronomical rate within the United States as well as internationally. According to the Center for Disease Control and Prevention (CDC) (2016) an estimated 29 million people suffer with diabetes and 86 million are prediabetic within the United States (US). Without major interventions from the healthcare community,

According to the United States Library of Medicine, diabetes is a disease that occurs when the body does not make or use insulin correctly, therefore causing fluctuating amounts of glucose in the blood. Diabetes is a disease that affects millions of adults and children from various cultures. According to the American Diabetes Association (2014), someone is diagnosed with diabetes every 19 seconds. The Center of Disease Control and Prevention most recent statistical report indicated there were 29.1 million adults and children affected by diabetes. Those numbers are astounding. Unfortunately, the American Diabetes Association (2014) estimates by year of 2050, one out of three adults will have diabetes. Therefore, it is imperative that adults take aggressive measures to prevent this disease. By the same token, diabetes diagnosed in children and adolescent is becoming more prevalent every day. The American Diabetes Association (2014) reported there were about 216, 00 children in the United States with diabetes. It is predicted that one out three children will be diagnosed with diabetes in their life. The statistics for both adults and children with diabetes are frightening; however, early detection can help lower the risk of developing the debilitating effects of diabetes.

Diabetes is a growing concern and health challenge for the American people (b). Diabetes is a condition in which the body cannot react to insulin appropriately or either cannot produce insulin efficiently (w). “Without a properly functioning insulin signaling system, blood glucose levels become elevated and other metabolic abnormalities occur, leading to the development of serious, disabling complications” (w). There are numerous forms of diabetes amongst the nation, however, there are three main forms of diabetes. Most people have heard of type one diabetes, type two diabetes, and gestational diabetes because they are common. Type two diabetes deals with a resistance to insulin, while

Being diagnosed as type one diabetic, it creates multiple situations that require the patient to take responsibility to help control their disease. Receiving this type of diagnoses can restrict the opportunities for the patient and impede their comfort of life. “In 2012, 29.1 million Americans, or 9.3% of the population, had diabetes. Approximately 1.25 million American children and adults have type 1 diabetes” (ADA par.1). Thus being diagnosed as a type one diabetic is not a common incident, only affecting the few “unlucky” individual’s

Type 2 diabetes typically emerges in middle adulthood, a period of life where lifestyle patterns and behaviors have become firmly established and may require greater effort to change. Also, during the pre-complications phase of type 2 diabetes, and even in the early phase of complications, the patient is often asymptomatic. Driving forces that might motivate a patient to seek medical care - unpleasant symptoms and awareness and fear of a serious illness - are therefore not present to provide a sufficient level of threat and motivation to make changes.

Type 1 Diabetes Mellitus is a disease that occurs when insulin-producing beta cells of the pancreas are damaged or are being destroyed (Mahan, Escott-Stump & Raymond, 2012). The gradual destruction of the beta cells of the pancreas usually leads to complete insulin deficiency, which ultimately manifests itself in the following symptoms at clinical onset: “high blood glucose (hyperglycemia), frequent urination (polyuria), excessive thirst (polydipsia), and a significant amount of weight loss, dehydration, electrolyte disturbances and ketoacidosis”, requiring dependency of exogenous insulin in order to promote optimal glycemic control in order to prevent further more severe complications; such as, ketoacidosis, microvascular diseases, macrovascular diseases, neuropathy, or worse – Death (Mahan et al., 2012). Type 1 Diabetes Mellitus can result from two existing forms: 1. Immune-mediated diabetes Mellitus, which is characterized by autoimmune destruction of the beta cells of the pancreas and an idiopathic (unknown cause) commonly seen in ethnic groups of African or Asian descent (Mahan et al., 2012). Of all diagnosed diabetes cases, prevalence of Type 1 Diabetes Mellitus cases account for 5%-10%, and although onset may present itself at any age, 70% of cases are diagnosed in young adults (younger than age 30), with a peak in occurring incidences seen mostly in children and adolescents (Mahan et al., 2012). “In the United States, approximately 1 in every 400

There are two main types of diabetes: Type 1 and Type 2. More than 15 million people in the United States have diabetes, but fewer than one million of those people have Type 1. Many people believe that there is no difference in the two but what they don’t know, is that there is. Type 1 Diabetes is a chronic autoimmune disease in which the immune system

There are over three million Americans that have already been diagnosed with type 1 diabetes, and another 15,000 children and 15,000 adults being diagnosed each year. Although frequently overshadowed by the better known type 2 diabetes, type 1 diabetes is an autoimmune disease that is not caused by “being fat” or “eating unhealthy” as many would ignorantly infer. Type 1 diabetes, however, is caused by the attacking of the immune system on the pancreas, denying it the ability to carry out its most important function, producing insulin to help control one’s blood glucose levels. For over a decade now, biomedical engineers, scientists, and doctors have been working diligently and effectively on creating a closed-loop

Type 1 diabetes is an autoimmune disease that begins when the pancreas quits making insulin. Insulin plays a key role by letting glucose enter the body’s cells, and then uses it for energy. When the body doesn’t get the

Type 1 diabetes (T1D) occurs when the pancreas produces little to no insulin, a hormone the body requires providing glucose with the ability to enter cells (Mayoclinic, 2014). It is the absorption of glucose that allows the body to manufacture its energy (Mayoclinic, 2014). T1D affects roughly 5-10% of patients with diabetes and is escalating annually by 2-5% (Medscape, 2014). T1D is a chronic condition that affects not only approximately 1 in every 400-600 children but 50% of those diagnosed develop T1D when they are older than 20 (Medscape, 2014; Tufts, 2014). This metabolic disease can be detected as early as 4 years old with the peak onset age between

Type 1 diabetes mellitus (T1DM) is the most common metabolic disorder in which both genetic and environmental factors are involved [1]. T1DM is considered a chronic immune-mediated disorder. It was hypothesized that whilst children have a genetic predisposition to T1DM, there is likely to be an environmental factor that triggers the development of T1DM. Possible triggers that have been suggested include viral infection, vaccines, low levels of vitamin D and cow’s milk, [2]. Oxidative stress is one of the important pathways that have been involved in the etiopathogenesis of T1D [3]. Complications of T1DM could be due to the cellular metabolism leading to hyperglycemia and excess production of reactive oxygen species (ROS).