2. List glycosaminoglycans (GAGS), indicate disaccharide subunits that make up structure and define their occurrence in the human body: GAGS Disaccharide subunits Occurrence in the human body
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- 18. peptidiase complete the digestion of peptides to amino acids От F 19. amylose it has B (1-4) glycoside bond От O F 20. clycine are non essential amino acids От O F2. Classification of amino acids: a) by the structure of carbon chain; b) by the position of amino group; c) by the presence of functional groups; d) by the polarity of the radical; e) by the ability to be synthesized in the human body.4) A polypeptide is subjected to the following digestion procedures and the fragments were sequenced. What is the sequence of the original peptide? Cyanogen bromide Trypsin digestion Asp-lle-Lys-Gln-Met Lys-Phe-Ala-Met Tyr-Arg-Gly-Met Gln-Met-Lys Gly-Met-Asp-lle-Lys Phe-Ala-Met-Lys and Lys Tyr.Arg Sequence of original peptide:
- 9. A daily diet of a 55-ycar-old woman, consisted of a 500 g of carbohydrates, 100 g of animal fats and 150 g of proteins, at the background of low physical activity. What possible consequences for the lipid metabolism such lifestyle could trigger? For the answer: a) compare the daily food consumption of the patient with the norm for this age and level of physical activity; b) draw the scheme of TAG synthesis in the liver and continue with their following transport to the tissues; c) draw the scheme of metabolic pathways which are more active in adipocytes of this patient compared with an individual of the same age consuming balanced dict; d) name the biologically active molecules released by adipocytes of this patient.1. The biological value of cellulose for the gastrointestinal tract.2. How many calories we need for excretion toxic nitrogenous waste due to 200g Protein?
- S1.What functional group (pictured below) is used in the formation of ATP, the backbone of DNA, and the plasma membrane? R. - HO- asluolom OgH 910m ansa obyd to inuoms adisi69 101 P- Hnedenoi HO 9tom anisinos H 19w 1639 eniv blut viend ou nontel:oceansied bol-ngtsl s19 1591 a. Amino b. Carbonyl c. Ester d. Phosphate e. Alcohol Sabios onime Tertio of bensemoo Insietib ti aolem tsrll blas onims ns to neg at to quang ly snodibod for ogh quotg1. Using an arrow, draw the site of cleavagr for the following peptides that are reacted by: Pepsin (a- b), trypsin (c-d), and chymotrypsin (e). H H H H H NH2 а. PEPTIDE VPQFAGI H H HN, H b. PEPTIDE DLIPAE .....8. Refer to the molecules shown below for the following questions: А. В. HO- HN- HO Il. H H HO H HO O., H. С. D. OH но HO, H OH H H. H HO "OH HO a. Name the above molecules. b. Which one/s is/are primary, and which one/s is/are secondary bile acids/salts? c. Name the molecules that will result from the action of intestinal bacteria on molecule A? d. Which one of the above molecules is the best emulsifier? Explain why.
- VI. Although most biologically relevant sugars have the D-configuration, L-fucose is a commonly observed monosaccharide component in glycoproteins. Glycosylated antibodies (IgGs) observed in patients with active TB have more fucose than those found in patients with latent TB (Lu et. al., 2016). Latent TB occurs when a person has the TB bacteria, but bacterial proliferation is kept under control by the body's immune system; hence, the infected person is asymptomatic and not infectious. A person with latent TB will test positive for the tuberculin test or TB blood test. a) L-fucose is also known as 6-deoxy-L-galactose. Note that D-galactose is a C-4 epimer of D-glucose. Draw the Fisher projections for D-glucose, D-galactose and L-fucose. (Hints: D- and L-isomers are enantiomers. 6-deoxy means that the hydroxyl group at C-6 is removed leaving just the methyl group). D-galactose: D-glucose: L-fucose (6-deoxy-L-galactose): b) L-fucose can cyclize into a pyranose and form two anomers. Draw…1. Where’s Elvis? Translate the following amino acid sequence into one – letter code: Glu – Leu – Val – Ile –Ser – Ile – Ser – Leu – Ile – Val – Ile – Asn – Gly – Ile – Asn – Leu – Ala – Ser – Val – Glu – Gly – Ala – Ser.___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___ ___Rank these amino acids from most to least hydrophobic. H #3 13N-C-H CH₂OH 1 Q .000 OB) 3>2 > 1 E D A) 1>3>2 C) 3 >1 > 2 $ 4 R F % 5 coo™ H₂N-C-H T + __8_5 A CH 2 CH₂ CH₂ 3 2 6 CH MacBook Pro Y & 7 G | H U * 00 8 J 1 + _000 H₂N-C-H CH ₂ 1 CH₂ _000 9 3 K O 0 L d