8. Organometallic reagents, such as organolithium (RLi), Gilman or Organo-cuprates (R2)CuLi) and Grignard (R MgBr), have been known to transform ketones and aldehyde molecules. Pages 1032-1033 show these reagents can modify acid chlorides, acid anhydrides and esters. OR Given the reactions below, provide the missing products, indicate the likely intermediates and explain all routes yield a alcohol. ÇI 1. LİCH3, ether, rt 2. H;O* 1. CH,CH,MgBr, diethyl ether 2. НС, Н,О 1. (PHCH2),CuLi, THF Ph 2. HCС, Н,О

8. Organometallic reagents, such as organolithium (RLi), Gilman or Organo-cuprates (R2)CuLi) and Grignard (R MgBr), have been known to transform ketones and aldehyde molecules. Pages 1032-1033 show these reagents can modify acid chlorides, acid anhydrides and esters. OR Given the reactions below, provide the missing products, indicate the likely intermediates and explain all routes yield a alcohol. ÇI 1. LİCH3, ether, rt 2. H;O* 1. CH,CH,MgBr, diethyl ether 2. НС, Н,О 1. (PHCH2),CuLi, THF Ph 2. HCС, Н,О

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter10: Alcohols

Section: Chapter Questions

Problem 10.50P

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Complete the reaction scheme below by filling in missing reagents and/or intermediate products for each step. Please explain.
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In the following reaction Series, write down the appropriate reagents that can be used where there are question marks
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