A 8 month old girl is taken into the emergency room a few days after receiving her first round of vaccines. She is experiencing a high fever, enlarged lymph nodes, and has been having diarrhea. After a blood test it revealed that she has an elevated level of immunoglobulin D and immunoglobulin A. What disease is likely to have caused this episode and which enzyme is affected? How does that influence biosynthetic pathways?

A 8 month old girl is taken into the emergency room a few days after receiving her first round of vaccines. She is experiencing a high fever, enlarged lymph nodes, and has been having diarrhea. After a blood test it revealed that she has an elevated level of immunoglobulin D and immunoglobulin A. What disease is likely to have caused this episode and which enzyme is affected? How does that influence biosynthetic pathways?

Anatomy & Physiology

1st Edition

ISBN:9781938168130

Author:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Publisher:Kelly A. Young, James A. Wise, Peter DeSaix, Dean H. Kruse, Brandon Poe, Eddie Johnson, Jody E. Johnson, Oksana Korol, J. Gordon Betts, Mark Womble

Chapter18: The Cardiovascular System: Blood

Section: Chapter Questions

Problem 35CTQ: A patient was admitted to the burn unit the previous evening suffering from a severe burn involving...

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Part || – An Unexpected Visitor After Ivy was finished meeting with Dr. Alvarez, she didn't feel like going back to her dorm room where her room- mates were waiting to hear from her. She decided to process her diagnosis at the local coffee shop. Curling up in an oversized chair with a warm cookie and peppermint hot cocoa with whipped cream always made her feel better. Sitting alone would give her time to think. How could something so important go so wrong in her cells? How did cells get or make the mitochondria anyway? Obviously, cells could survive without mitochondria if they had to, so why had mitochondria evolved in the first place? Just then, Ali, a fellow student in her biology class who made it a point to sit near her each class, walked over to strike up a conversation. "Hi Ivy! Whať's up?" Trying to avoid conversation, Ivy simply shrugged and mumbled, “Not much." Ali gave her a big smile and said "I've noticed that you take good notes in bio, would you want to study together...…
(60). A 3 year old boy is evaluated because he had recurrent episodes of otitis media, an episode of pneumonia, and chronic diarrhea since he was 6 months of age.His height is in the 10th percentile and his weight is in the 8th percentile. Serum IgM concentration is increased and serum IgG, IgA and IgE concentrations are markedly decreased. Which of the following molecules is most likely deficient in this patient? (A) C1 inhibitor (B) C8 (C) CD 40 ligand (CD 154) (D) interleukin-2 (IL-2) receptor gamma chain (E) NADPH oxidas
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Experiment This experiment was designed to analyze the structure of a component (C3c protein) of the complement system, which is involved in the immune response against microorganisms. Purified C3c protein (molecular mass: 145 kd) was incubated in the presence of various concentrations of the reducing agent dithiothreitol (DTT) and then subjected to electrophoresis in a sodium dodecyl sulfate (SDS)-polyacrylamide gel. SDS disrupts noncovalent bonds and polypeptides are separated by size during electrophoresis. The gel was stained with Coomassie Brilliant Blue, a protein dye. The figure shows the molecular masses of intermediates and products generated by DTT treatment. Results: Molecular mass (kd) 145- 102- 75- 43- 27- [DTT] (MM) 10.00 1 2 3 4 5 6 Samples Questions 1. How many polypeptides are present in C3c? Determine their molecular masses from the figure. What was the purpose of using DTT in this experiment? What kind of bonds hold the polypeptides 2. 3. together? 4. How is the 102…
Experiment This experiment was designed to analyze the structure of a component (C3c protein) of the complement system, which is involved in the immune response against microorganisms. Purified C3c protein (molecular mass: 145 kd) was incubated in the presence of various concentrations of the reducing agent dithiothreitol (DTT) and then subjected to electrophoresis in a sodium dodecyl sulfate (SDS)-polyacrylamide gel. SDS disrupts noncovalent bonds and polypeptides are separated by size during electrophoresis. The gel was stained with Coomassie Brilliant Blue, a protein dye. The figure shows the molecular masses of intermediates and products generated by DTT treatment. Results: Molecular mass (kd) 145- 102- 75- 43- 27- [DTT] (MM) 1 2 3 4 5 6 Samples Questions 3. What kind of bonds hold the polypeptides together? |
Experiment This experiment was designed to analyze the structure of a component (C3c protein) of the complement system, which is involved in the immune response against microorganisms. Purified C3c protein (molecular mass: 145 kd) was incubated in the presence of various concentrations of the reducing agent dithiothreitol (DTT) and then subjected to electrophoresis in a sodium dodecyl sulfate (SDS)-polyacrylamide gel. SDS disrupts noncovalent bonds and polypeptides are separated by size during electrophoresis. The gel was stained with Coomassie Brilliant Blue, a protein dye. The figure shows the molecular masses of intermediates and products generated by DTT treatment. Results: Molecular mass (kd) 145- 102- 75- 43- 27- [DTT] (MM) 10.00 1 2 3 4 5 6 Samples Questions 4. How is the 102 kd polypeptide related to the other polypeptide species?
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the formation of blood clots and is taken regularly by individuals with a heart condition. Steroids such as cortisol are used to control some autoimmune diseases and severe arthritis by down regulating the inflammatory response. After reading the role of inflammation in the bodys response to infection, can you predict an undesirable consequence of taking anti inflammatory drugs on a regular basis?