A patient arrives at the ER complaining of seizures. The patient is taking phenytoin as prescribed which has a therapeutic range of 10-20 ug/mL. You order the SDC and find it is 8 ug/mL at steady state. This is an indication that · ■ A) dose needs to be increased. The dose needs to be individualized. B) The patient is noncompliant.
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- Your doctor is determining which drug would best treat your ailment - a drug with a low dissociation constant and a few significant side effects or a drug with a high dissociation constant and many mild side effects. There's no perfect choice, so they go with the first choice. What does this mean for you? A) You'll need a relatively low dose of the drug to be effective and chances of side effects are low B) You'll need a relatively high dose of the drug but the chances of side effects are low. C) You'll need a relatively high dose of the drug but the side effects are not expected to be harmful D) You'll need a relatively low dose of the drug but the risk of side effects is high.1. The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is 30 1/hr and its volume of distribution is 1501. a) What infusion rate will be necessary to reach the target concentration? b) How long will it take to reach steady state? c) What loading dose will be required to instantaneously achieve the steady state?Regarding Ritalin: What is the class of the drug?What is the mechanism of action?What is the Receptor siting the drug targets?What is the drug's main effect?What are the unexpected effects and side effects and drug interactions?What are the non-FDA uses of the drug?
- a.) Name some common symptoms that over-the-counter medicines can reduce. b.) What information is needed to accompany the medication? C.) What do you mean by side effects? Give examples.Why anesthesiologist often prefer combined uses of GA instead of single agent?27. In a life-threatening situation when a therapeutic concentration of a drug is needed immediately, which of the following is the best means for choosing the loading dose? A) Bolus of five times the maintenance dose B) Infusion at five times the normal maintenance rate for 1 half-life C) Maintenance dose times body weight D) Maintenance doses with the dose interval equal to the half-life E) Steady-state plasma concentration times the volume of distribution
- The desire steady state concentration of a drug is 5mg/l. Clearance of the drug is30 l/hr and its volume of distribution is 150l.a) What infusion rate will be necessary to reach the target concentration?b) How long will it take to reach steady state?c) What loading dose will be required to instantaneously achieve the steady state?After a nebulizer treatment with the beta agonist albuterol, the patient complains of feeling a little “shaky,” with slight tremors of the hands. The patient’s heart rate is 98 beats/min, increased from the pretreatment rate of 88 beats/min. The nurse knows that this reaction is ana) expected adverse effect of the medication.b) allergic reaction to the medicationc indication that he has received an overdose of the medication.d) idiosyncratic reaction to the medication.Several patients have standard orders for acetaminophen as needed for pain. When the nurse reviews their histories and assessments, the nurse discovers that one of the patients has a contraindication to acetaminophen therapy. Which patient should receive an alternate medication? a )A patient with a fe-er of 103.4° F (39.7° C) b )A patient admitted with deep -ein thrombosis c )A patient admitted with se-ere hepatitis d )A patient who had abdominal surgery 1 week earlier
- The nurse caring for a patient who is receiving betal agonist drug therapy needs to be aware that these drugs cause which effect? a )Increased cardiac contractility b) Decreased heart rate c )Bronchoconstriction d)Increased Gl tract motilitySuggest FOUR possible strategies to cross the blood–brain barrier (BBB) for drug delivery.PO Aav DAV == AaBbCcDdEe AaBbCcDdEe AaBb CcD AaBbCcDdE Normal M H No Spacing Heading 1 Heading 2 Question 5 a) Explain the general principles by which medical images may be obtained through the use of radiopharmaceuticals and a gamma camera. b) Explain the use of radiopharmaceuticals in i) Myocardial perfusion scans ii) Skeletal scintigraphy 20 ¶