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- A patient is required to take Allegra 120mg daily. How many grams of this drug will the patient take in 5 days? Showing dimensional analysis?Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives. The given question to me is: What is a pharmacopeial monograph? Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives.Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. How the cracking is occurring in the emulsions? If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examples
- Enumerate and describe the classes of enantiomeric drug Discuss briefly the different methods of enantioanalysis. Give the advantage of using potentiometry over chromatographyEnumerate and describe at least three (3) big scale pharmaceutical methods on reducing particle size.Specificity Specificity is the ability to measure accurately and specifically the analyte of interest in the presence of other components that may be expected to be present in the sample matrix. It is a measure of the degree of interference from such components, as other active ingredients, excipients, impurities, and degradation products, insuring that a peak response is due to a single component only. Experimental Dissolve amount of paracetamol (20 µg/ml) powder in three different volumetric flasks containing IN HCI, IN NaOH and 6% H₂O2 respectively, then keep your solution overnight in a fume hood. Analysis your solution by injecting three times each solution and calculates the recovery% 1 N HCI Peak area Actual exp. conc. Recovery% IN NaOH 6% H₂O2
- Consider the following from the Ampicillin for Injection, USP package insert: For Intramuscular Use: Label Claim 250mg 500mg 1g 2g Amount of Diluent (mL) Approx. Volume (ml) 0.9 1.7 3.4 6.8 1 2 4 8 a) What is the amount of diluent needed to reconstitute a 1 g vial? b) What is the powder volume for a 1 g vial of ampicillin? Approx. Concentration (mg/mL) 250 250 250 250 Later in the package insert you see: For Direct Intravenous Use: Add 5 mL Sterile Water for Injection or Bacteriostatic Water for Injection to the 250 and 500 mg vials and administer slowly over a 3 to 5-minute period. Ampicillin for Injection, 1 g or 2 g, may also be given by direct intravenous administration. Dissolve in 7.4 or 14.8 mL Sterile Water for Injection or Bacteriostatic Water for Injection, respectively, and administer slowly over at least 10 to 15 minutes. c) What is the amount of diluent needed to reconstitute a 1 g vial of ampicillin for direct IV injection d) What is the total amount of volume that will…Available cloxacillin 2g match the following reconstitution option with the order ordered: 1500 mg of cloxacillin IV q8h ordered: 800 mg of cloaxacillin IM q6h ordered: 500 mg of cloxacillin IM q8h ordered: 1800 mg of cloxacillin IV q8h 1. 2. add 4.8 mL sterile water for concentration of 400mg/mL add 9.8 mL of sterile water for concentration of 200 mg/mLState the principle that underlies the following biochemical tests: a) Methyl red test b) Voges-Proskauer test
- List the pros and cons of using commercial powder media such as RPMI-1640.Give one advantage and one disadvantage of pharmaceutical solid dosage forms. Explain each advantage and disadvantage thoroughly.Give the drug examples of emulsion prepare by these method:- 1)dry gum method 2)wet gum method 3)bottle gum method