Match the antibody isotype with its functional characteristics. Highly effective at activating complement, too large to get to infected tissues Crosses cells, including the placenta, neutralizes toxins Dimeric form crosses the intestinal epithelia using PlgR Crosslinking on the surface of the mast cell leads to degranulation and release of histamine Although the exact function of this isotype is unknown, we know it does NOT fix complement ✓Choose... IgD IgM IgG IgA IgE Choose...

Match the antibody isotype with its functional characteristics. Highly effective at activating complement, too large to get to infected tissues Crosses cells, including the placenta, neutralizes toxins Dimeric form crosses the intestinal epithelia using PlgR Crosslinking on the surface of the mast cell leads to degranulation and release of histamine Although the exact function of this isotype is unknown, we know it does NOT fix complement ✓Choose... IgD IgM IgG IgA IgE Choose...

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter34: Immunity

Section: Chapter Questions

Problem 7SA

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Match the term with its correct description Long, flexible molecule expressed on B-cells, macrophages and FDC which binds to C3d B-cell co-receptor Cognate pair Rapidly dividing cell which is going through somatic hypermutation Slowly dividing cell which searches for antigen match on FDC ✓Choose... CR2 Centrocyte CR2, CD19, CD81 TFH cell and B-cell which recognize same antigen Centroblast Choose... Choose... S
Match the hypersensitivity to the description. Туре 1 [ Choose| [ Choose] Memory T helper cells release cytokines that recruit and activate macrophages. Antibodies bound to antigens that cause mast cell and PMN degranulation. Туре 2 against cell surface antigens, such as in blood transfusions. IgE mediated and can manifest as eczema or asthma. Туpe 3 [ Choose ] Туpe 4 [ Choose ]
1 2 3 4 5 6 Antibodies derived from 3 of Toxins Viruses are secreted by /0 Antibodies bind to Antigens causing Opsonization enhancing 5 Drag terms from the right to the boxes below. Click "Submit to check your results. are grouped into S classes are also known as 8 Complement activation enhancing-// lysing- 12 7 899600- 10 11 12 13 enhancing Phagocytosis Reset ✔ Submit Agglutination Antigen-stimulated B cells IgA igD IgE IgG IgM Immunoglobulins Inflammation Neutralization Phagocytosis Plasma cells Target bacteria Also called death by oxidation
pathogenic bacteria in gut lumen binds binds capture and transfer to A B submucosa inhibits binds produces produces epithelial cells of small intestine klocated below B-cll follicle in Peyer's patches reside on reside presents among antigens E F capture and transfer from lumen presents engulf antigens pathogenic bacteria in gut submucosa D -lyse-
DRAW IT Sketch a B cell antigen receptor. Label the Vand C regions of the light and heavy chains. Label theantigen-binding sites, disulfide bridges, and transmembrane region. Where are these features located relativeto the V and C regions?
Match the term with its correct description. selection for thymocytes which recognize self MHC molecules elimination of thymocytes which recognize self continued alpha chain rearrangement until a functional TCR is generated process by which autoreactive thymocytes are eliminated in the thymus activation of a T-cell only if the appropriate MHC molecule presents an antigenic peptide ✓Choose... Apoptosis MHC restriction Positive selection Negative selection T-cell receptor editing Choose...
eds Antibodies (Immunoglobulins) Objective 14 Antibodies (immunoglobulins) are glycoproteins secreted by plasma cells. They are located in interstitial fluid, plasma (gamma globulin fraction) and in body secretions. onse A. Antibody Structure Heavy chain Antigen-binding site Light chain Insmakamos Hinge region Complement- binding site Stem region Macrophage binding site OHO (a) Antibody molecule OHO X = Disulfide bond Carbohydrate four polypeptide chains (two heavy, two light) chains are held together by covalent disulfide bonds (S=S) each heavy chain and each light chain has two functional areas: consists of highly variable amino acid sequences which forms the basis of antibody specificity; antigen binds here ????? to more conserved amino acid sequences; there are five basic sequences of amino acids, which define the 5 antibody classes (IgG, IgA, IgM, IgE and IgD); ????? each class has its own characteristic set of effector functions (see next page) Your notes: 4 40 4. 39
%VY lI, نقطة واحدة Q/ finger-like projections that arise from the epithelial layer in some organs are called Cilia Villi Microvilli Non of the above ösly äbäi Q/ The cell of connective tissue that contain serotonin to immediate * hypersensitivity is Histiocyte cell Mast cell Adipose cell Fibroblast cell هذا السؤال مطلوب صفحة 2 من 3 التالي II >
Based on the five major classes of antibodies given below, which of the following is present on the membrane of naive B cells? Select all that may apply. O IgD O IgA O IgM O IgG O IgE
TABLE 6 | Correlation between immune markers and age. Marker NCI PAN LCI LP NK activity (lysis %) R Spearman -0.406 -0.305 -0.239 -0.204 -0.016 Р 0.004 0.035 0.101 0.165 0.913 NCI, Neutrophil Chemotaxis Index; PAN, phagocytic activity of neutrophils; LCI, Lymphocyte Chemotaxis Index; LP, lymphocyte proliferation; NK, natural killer. p is the associated value to the corresponding statistical test.
Complement is an integral part of the innate immune response to bacteria . One of its mechanisms of action is to behave as an anaphylatoxin Describe the anaphylatoxic effects of complement identifying which components are activated.
b) Figure 14 shows a part of acquired immune response. Pathogen P Antigen fragments MHC Antigen гесeptor. CD4 Helper T cell Activated helper T cell Figure 14 i) Describe the above process. II) Why do O and P have different pathways for antigen processing although the same antigen is identified? iii) What are the effects on P when activated helper T cell releases Q7