Match the antimicrobial drug class to its action. 1. Macrolides A. Inhibit cell wall synthesis 2. Tetracyclines B. Disrupt cell membrane integrity 3. Quinolones C. Block folic acid synthesis 4. Sulfa Drugs D. Interrupts nucleic acid synthesis 5. Penicillins E. Inhibits protein synthesis 6. Polymyxin
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- Many antimicrobials were discovered in the first half of the 20th century. Match the early antimicrobial drugs with their description and/or target disease: salvarsan sulfanilamide penicillin prontosil Choices - first synthetic antimicrobial synthetic dye used to treat streptococcal and staphylococcal infections treatment for syphilis first discovered natural antibioticlist 3 different mechanisms of antibacterial drugs. Example: acting on cell wall, cell membrane, etcWhich of the following would not be a potential side effect of standard antimicrobial drugs? disruption of the host's normal microbiota damage to the host's kidneys allergic reactions in the host inhibition of host protein synthesis
- 1) It is sometimes best to use two different antibiotics in order to treat an infection. This might happen because of the : -Symbiotic effects of the drugs -Synergistic effects of the drugs -Antagonistic effects of the two drugs 2) What was the first synthetic antimicrobial? - Salvarsan - Tetracycline - Sulfonimidemost of the available antimicrobial medicaitons are effective against: a. bacteria b. protozia c. fungi d. viruses e. all of the about about equallyI am an agent that can cause human disease but under normal circumstances am unlikely to be a serious hazard to laboratory workers, the community, livestock or the environment. Effective treatment and preventive measures are available. What is my risk factor?
- A group of patients entered the hospital unconscious. All patients are employees of a chemical plant, where mass poisoning with cyanide compounds occurred. Questions: 1. The development of which kind of typical pathological process (TPP) is initiated by intoxication with cyanides? 2. Define this TPP. 3. What kind of TPP according to the pathogenetic classification has developed in patients? 4. Describe the mechanism of formation of this type of TPP. 5. List the changes in blood gas composition and pH at this form of TPP. 6. How can you explain these changes in blood gas composition and pH? 7. What kind of tissue cell death is typical in this case?Item 20 Identify an accurate statement about antimicrobial drugs. Absorption of daptomycin from the GI tract is excellent. One of the most serious effects of metronidazole is bone marrow depression. Clindamycin is mainly indicated for anaerobic organisms. Chloramphenicol is the choice of drug for meningitis in infants.A patient is diagnosed with malignant Hymenolepis nana and HIV. The patient's CD4 cell count is 28 cells per cubic millimeter and the patient is nonadherent to HIV drugs. Why or why not would albendazole be effective in this case?
- Many antibiotics used in modern medicine are compounds made by fungi that inhibit bacterial protein synthesis. Describe the specific effect of the following antimicrobial drugs: (i) Tetracycline (ii) Puromycin (iii) Alpha-AmanitinReviewing drug characteristics, choose an antimicrobial for each ofthe following situations (explain your choice):a. for an adult patient suffering from Mycoplasma pneumoniab. for a child with bacterial meningitis (drug must enter intocerebrospinal fluid) c. for a patient who has chlamydiosis and an allergy to azithromycind. for PPNG drug-resistant gonorrheaGive two examples of antibiotics that act on the following: cell wall synthesis disruption of cell membrane interferes protein synthesis prevents DNA/RNA replication Disruption of formation of metabolites like Folic Acid