Match the following scientists with their contribution to the field of immunology: (each answer will only be used once) [Choose] Chris Garcia/David Garboczi Michael Heidelberger/Oswald Avery ✓BM and thymus required for graft rejection Developing B cells rearrange their DNA Disproved "induced fit* Ab binding theory Developed T cell-specific antibodies Antibodies are soluble proteins Cloned IL-2 (T cell growth factor) Gustav Nossal/Joshua Lederberg Genetic map of H-antigens for tissue rejection Crystal structure of TCR:MHC-peptide complex Showed T cells recognize both MHC and Ag [Choose Graham Mitchell /Jacque Miller Kendall Smith [Choose] Susumu Tonegawa [Choose] Rolf Zinkernagel/Peter Doherty [Choose ] George Snell/Peter Gorer [Choose] Lloyd Old/Edward Boyse [Choose ]

Match the following scientists with their contribution to the field of immunology: (each answer will only be used once) [Choose] Chris Garcia/David Garboczi Michael Heidelberger/Oswald Avery ✓BM and thymus required for graft rejection Developing B cells rearrange their DNA Disproved "induced fit* Ab binding theory Developed T cell-specific antibodies Antibodies are soluble proteins Cloned IL-2 (T cell growth factor) Gustav Nossal/Joshua Lederberg Genetic map of H-antigens for tissue rejection Crystal structure of TCR:MHC-peptide complex Showed T cells recognize both MHC and Ag [Choose Graham Mitchell /Jacque Miller Kendall Smith [Choose] Susumu Tonegawa [Choose] Rolf Zinkernagel/Peter Doherty [Choose ] George Snell/Peter Gorer [Choose] Lloyd Old/Edward Boyse [Choose ]

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter16: Antifungal, Antiviral, And Immunizing Agents

Section: Chapter Questions

Problem 18RQ

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eds Antibodies (Immunoglobulins) Objective 14 Antibodies (immunoglobulins) are glycoproteins secreted by plasma cells. They are located in interstitial fluid, plasma (gamma globulin fraction) and in body secretions. onse A. Antibody Structure Heavy chain Antigen-binding site Light chain Insmakamos Hinge region Complement- binding site Stem region Macrophage binding site OHO (a) Antibody molecule OHO X = Disulfide bond Carbohydrate four polypeptide chains (two heavy, two light) chains are held together by covalent disulfide bonds (S=S) each heavy chain and each light chain has two functional areas: consists of highly variable amino acid sequences which forms the basis of antibody specificity; antigen binds here ????? to more conserved amino acid sequences; there are five basic sequences of amino acids, which define the 5 antibody classes (IgG, IgA, IgM, IgE and IgD); ????? each class has its own characteristic set of effector functions (see next page) Your notes: 4 40 4. 39
Describe HOW the spike protein produced by your own cells results in an immune response, antibody production and memory! You will need to mention the cell receptors involved, the specific T-cells and "other" lymphocytes that are part of this process and explain how all of this leads to antibody production and circulation for three months. Need answer in short but ASAPLY
TABLE 6 | Correlation between immune markers and age. Marker NCI PAN LCI LP NK activity (lysis %) R Spearman -0.406 -0.305 -0.239 -0.204 -0.016 Р 0.004 0.035 0.101 0.165 0.913 NCI, Neutrophil Chemotaxis Index; PAN, phagocytic activity of neutrophils; LCI, Lymphocyte Chemotaxis Index; LP, lymphocyte proliferation; NK, natural killer. p is the associated value to the corresponding statistical test.
1 2 3 4 5 6 Antibodies derived from 3 of Toxins Viruses are secreted by /0 Antibodies bind to Antigens causing Opsonization enhancing 5 Drag terms from the right to the boxes below. Click "Submit to check your results. are grouped into S classes are also known as 8 Complement activation enhancing-// lysing- 12 7 899600- 10 11 12 13 enhancing Phagocytosis Reset ✔ Submit Agglutination Antigen-stimulated B cells IgA igD IgE IgG IgM Immunoglobulins Inflammation Neutralization Phagocytosis Plasma cells Target bacteria Also called death by oxidation
pathogenic bacteria in gut lumen binds binds capture and transfer to A B submucosa inhibits binds produces produces epithelial cells of small intestine klocated below B-cll follicle in Peyer's patches reside on reside presents among antigens E F capture and transfer from lumen presents engulf antigens pathogenic bacteria in gut submucosa D -lyse-
28 A =、三、|E |三v|v v A Shape Fill v x, AV v Aa v 三 =| 、申。 Convert to SmartArt Picture Shapes Text Вох Arrange Quick Styles Shape Outline provements, choose Check for Updates. Click to add title Compare and contrast the mechanisms of the innate and adaptive immune systems, using diagrams to illustrate your answer. E Notes Comments MAY 1 N 11 MacBook Air 000 F10 F11 F7 F8 F9 D00 FA F5 & 4 5 7 8 9. T. Y U %24
Determine which statement(s) are true/false NK cells are a type of lymphocyte involved in acquired immunity Plasma cells are a type of B- cell that directly bind antigens on target cells ✓ [Choose ] False True Binding of antigen to the cell surface of B-memory cells is a trigger for the secondary immune response Loss of MHC Class I expression would decrease the effectiveness of cytotoxic T-cell response [Choose ] [Choose ] [Choose ] >
Examine Type IV hypersensitivities by completing each sentence. 54 Туре IV МНС I tuberculin Compared to Type III hypersensitivities, reactions primarily involve -cell activity. T allografts Type IV dysfunction is known as secondary antigen exposure. hypersensitivity for symptoms arise 1 to several days following contact dermatitis delayed One example, infectious allergy, occurs during the reaction in persons sensitized by tuberculosis Lysosome infection. xenografts GVHD which occurs after exposure to antigens in The most common delayed allergic reaction, however, is plant resins, drugs, or personal articles, and involves the production of inflammatory cytokines that cause blistering. Autografts В -mediated reactions, while Finally, host rejection of grafted tissue can occur due to occurs when passenger cells in the grafted tissue attack host cells. MHC II Psoriasis
Match the term with its correct description. selection for thymocytes which recognize self MHC molecules elimination of thymocytes which recognize self continued alpha chain rearrangement until a functional TCR is generated process by which autoreactive thymocytes are eliminated in the thymus activation of a T-cell only if the appropriate MHC molecule presents an antigenic peptide ✓Choose... Apoptosis MHC restriction Positive selection Negative selection T-cell receptor editing Choose...
T-independent humoral immunity may be stunted in children because __________. View Available Hint(s) for Part A the repertoire of T cells in children is not fully developed T cells are overactive in children children have a weak ability to produce tumor necrosis factor the repertoire of B cells in children is not fully developed
Match the term with its correct description Long, flexible molecule expressed on B-cells, macrophages and FDC which binds to C3d B-cell co-receptor Cognate pair Rapidly dividing cell which is going through somatic hypermutation Slowly dividing cell which searches for antigen match on FDC ✓Choose... CR2 Centrocyte CR2, CD19, CD81 TFH cell and B-cell which recognize same antigen Centroblast Choose... Choose... S
Discuss the differences between humoral and cell mediated immunity in terms of chemicals and cells involved in each process as they tackle pathogens. (please do this on text as i cant read writing the best) and also in paragraphs and not a table if possible thank you!)