NH2 NH2 NH2 NH2 C=N C=N C=N C=N-H pk-2.17 -H* pk- 8.00 -H* pK H. H. - 12.5 NH NH | H (CH)3 NH | (CH2)3 NH | (CH3 -H* H (CH)3 +H +H H-N+-C-COOH H-N+-C-COo- H2N-C-coo H2N-C-CO- H H H II IV

Body Structures & Functions Updated
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ISBN:9780357191606
Author:Scott
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Chapter12: Blood
Section: Chapter Questions
Problem 1RQ
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The amino acid arginine ionizes according to the following scheme:                  (a) Calculate the isoelectric point of arginine. You can neglect contributions
from form I. Why?
(b) Calculate the average charge on arginine when pH = 9.20.
(c) Is the value of average charge you calculated in part b reasonable, given
the pI you calculated in part a? Explain your answer.

NH2
NH2
NH2
NH2
C=N
C=N
C=N
C=N-H
pk-2.17
-H*
pk- 8.00
-H*
pK
H.
H.
- 12.5
NH
NH
|
H (CH)3
NH
|
(CH2)3
NH
|
(CH3
-H*
H (CH)3
+H
+H
H-N+-C-COOH
H-N+-C-COo-
H2N-C-coo
H2N-C-CO-
H
H
H
II
IV
Transcribed Image Text:NH2 NH2 NH2 NH2 C=N C=N C=N C=N-H pk-2.17 -H* pk- 8.00 -H* pK H. H. - 12.5 NH NH | H (CH)3 NH | (CH2)3 NH | (CH3 -H* H (CH)3 +H +H H-N+-C-COOH H-N+-C-COo- H2N-C-coo H2N-C-CO- H H H II IV
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