ollowing is an outline for a synthesis of the anorexic (appetite suppressant) fenflura- mine. This compound was one of the two ingredients in Phen-Fen, a weight-loss prep- aration now banned because of its potential to cause irreversible heart valve damage. N-OH `NH2 CF3 CF3 CF3 CF3 `CF3 CF3 Fenfluramine

Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter19: Enolate Anions And Enamines
Section: Chapter Questions
Problem 19.68P
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Is fenfluramine chiral? If so, which of the possible stereoisomers are formed in this synthesis?

ollowing is an outline for a synthesis of the anorexic (appetite suppressant) fenflura-
mine. This compound was one of the two ingredients in Phen-Fen, a weight-loss prep-
aration now banned because of its potential to cause irreversible heart valve damage.
N-OH
`NH2
CF3
CF3
CF3
CF3
`CF3
CF3
Fenfluramine
Transcribed Image Text:ollowing is an outline for a synthesis of the anorexic (appetite suppressant) fenflura- mine. This compound was one of the two ingredients in Phen-Fen, a weight-loss prep- aration now banned because of its potential to cause irreversible heart valve damage. N-OH `NH2 CF3 CF3 CF3 CF3 `CF3 CF3 Fenfluramine
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