Suppose that you have cancer cell line X was treated with drug Y to increase the expression levels of protein Z which is a tumor suppressor gene. Explain How can you study protein Z in these cells?

Q: You are curious to identify the region of the gene X sequence that serves as an enhancer for gene…

A: Nascent RNA (ribonucleic acid) sequencing analysis is a tool for enhancer identification. Some…

Q: Oncogenes show a of mutation, while tumor suppressor genes show a of mutations. is the process by…

A: Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread…

Q: Define tumor-suppressor genes. Why is a mutated single copy of a tumor-suppressor gene expected to…

A: The repeated and uncontrollable division of cells forms a large mass called the tumor. Tumors might…

Q: Genes that cause cancer are called _____________.

A: Cancer means uncontrol cell proliferation and division in the body. This uncontrolled group of cell…

Q: Could a gene be involved in the growth of both stem cells and some kinds of cancer? Explain your…

A: in stem cells we have an important class of genes called proto-oncogenes [PO] with are necessary for…

Q: explain how p53 functions in a cell that sustained DNA damage to prevent progression of that cell…

A: p53 induces numerous different target genes and blocks the different stages of progression of tumor…

Q: Several new cancer drugs inhibit the enzymes that either put acetyl groups on histones or take them…

A: Cancer in simple term can be referred to a set of diseases which are caused by the production of an…

Q: What is the difference between an oncogene and a tumor-suppressor gene? Give some examples of the…

A: Cell proliferation, cell differentiation, and cell survival are under the control of some critical…

Q: Changes in chromatin packing correlate with changes in gene expression in most cells.  Why do you…

A: The chromosomes resemble a mass of extremely fine tangled string called chromatin, consisting of DNA…

Q: Cancer cells removed from a patient's tumor have increased gene expression of several hundred genes…

A: Cancer  Cancer if a kind of disorder which caused by several means like drug, radiation, malfunction…

Q: what is the role and relevence of chromatin in gene expression

A: Chromatin: It is the mass of genetic materials composed of DNA and Proteins which are condensed to…

Q: Explain how mutations in oncogenes and in tumor suppressorgenes cause cancer.

A: Cancer is a group of diseases that involves abnormal growth of the cell. These cells have the…

Q: Explain the role of p53 protein in protecting normal cells against cancer. With respect to this…

A: The cell is the primary unit of all living entities. The normal cell undergoes some necessary…

Q: Define tumor-suppressor genes. Why is a mutation in a single copy of a tumor-suppressor gene…

A: Tumor-supressor genes: Tumor-suppressor genes is defined as normal genes that will slow down the…

Q: The figure below represents a cell undergoing gene expression. Use the figure to answer the…

A: Ans- a) 2) labeled as exons b) 3) Labelled as Introns c) Genes are the structural and functional…

Q: Although tobacco smoking is responsible for a large number of human cancers, not all smokers develop…

A: Cancer refers to the uncontrolled cell division caused by the mutations in the genes which control…

Q: Mutations in the RB gene are often associated with cancer. Explain how a mutation that results in a…

A: The cell cycle is the series of stages that allow the cell to pass from one cell division to…

Q: Explain why cells need to control gene expression.

A: Gene expression is the process in which the functional gene is produced by the gene containing…

Q: What is the difference between an oncogene and a tumor-suppressorgene? Give two examples of each…

A: Cancer is defined as the biological disorder in which the cells undergo uncontrolled growth and cell…

Q: Which of the following is not a tumor suppressor gene? a.RET b.RB c.BRCA1 d.BRCA2

A: A normal cell undergoes regulated division, differentiation, and apoptosis (programmed cell death).…

Q: The normal copies of tumor-suppressor genes encode proteins that have which three types of…

A: A tumour suppressor gene also known as anti-oncogene is a gene that is responsible to regulate the…

Q: How can a mutation in a tumor-suppressor gene contribute to the development of cancer?

A: Tumor-suppressor genes are like any other normal genes whose functions include slowing down cell…

Q: Describe, using specific examples, the differences in how a growth factor gene and a tumor…

A: When we talk about cancer, there are certain genes associated with it. Oncogenes are genes that are…

Q: A research study indicated that an agent in cigarette smoke caused the silencing of a tumor…

A: The TP53 gene provides instructions for making a protein called tumor protein p53 (p53). This…

Q: Explain how can you  study protein Z components? (needed)

A: The proteins are the macromolecules and these structures are so so small that they can be seen by a…

Q: What does the statement above mean

A:

Q: IS most suppressor gene that is often mutated in human cancers.

A: Tumor suppressor genes are also known as anti oncogenes because they regulate the cell cycle during…

Q: In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an…

A: Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when…

Q: Proteins that actively protect cells from progressing toward cancer are called _____________.

A: A tumor suppressor is the regulation of cell division by keeping cells from proliferating  ( growing…

Q: Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell…

A: p53 is a tumor suppressor gene but if p53 gets mutated then this protein is not able to bind to the…

Q: Explain How can you study the protein Z in the cancer cells?

A: In case of cancer, the activity of the hemostatic system components triggers tumor growth and…

Q: Let’s suppose you were interested in developing drugs to preventepigenetic changes that may…

A: Genes are basic physical and functional unit of heredity. It is a part of DNA that has instruction…

Q: Cells in a tumor contain mutated copies of a particular gene that promotes tumor growth. Gene…

A: An oncogene helps in control cell division and  contributes to cancer progression whereas a tumor…

Q: Under normal physiological conditions, proto-oncogenes and tumor suppressors help control cell…

A: A significant contrast among the oncogenes and tumor suppressor genes is that oncogenes result from…

Q: Why don’t all loss-of-function mutations that are recessive at the cellular level behave as…

A: Loss of function mutation is otherwise known as inactivating mutations. This type of mutation is…

Q: New drugs are being developed that decrease DNA methylation and prevent the removal of acetyl groups…

A: Introduction  Chromatin fibre can be classified into two types based on the condensation:…

Q: Explain how epigenetic changes can contribute to tumorigenesis.

A: Tumors are clumps of cells formed by uncontrollable cell division. Tumorigenesis is the uncontrolled…

Q: Describe the molecular mechanisms involved in P53’s role as a tumor repressor protein

A:

Q: Do mutations that cause cancer in an individual pass down to his/her offspring? What is the role of…

A: Cancer is the umbrella term for a group of diseases. Any of the body's cells begin to divide without…

Q: Compare and contrast oncogenes versus tumor-suppressorgenes.

A: Cancer is the uncontrolled proliferation of cells that can be treated by chemotherapy and…

Q: a. How could you use sequence analysis to determine if this patient inherited the mutation from one…

A: There are various diagnostic technique used to diagnose cancer and they are:- Biopsy, Breast MRI,…

Q: how would the disruption of the Rb family of proteins lead to cancer? Describe the possible…

A: Please follow step 2 for detailed explanation.

Q: Some cancers have been treated with drugs that demethylate DNA.Explain how these drugs might work.…

A: Cancer is a disease that is associated with genetic changes. The mutations in the oncogenes and…

Q: Imagine you have used cBioportal and breast cancer patient datasets and identified a…

A: Introduction :- Cancer is defined as the uncontrolled and un-regulated proliferation of cells , due…

Q: Explain the difference between a proto-oncogene and a tumor-suppressor gene.

A: Cancer is the state of uncontrolled cell division.