Answered: The response the AI gave me contains…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The following is an assignment question I wrote and then submitted to the AI chatbot – ChatGPT: a poly glutamic acid peptide can form an alpha helix at pH 2.4 but not at pH 7.5, why? Here is the response the AI gave me: “Poly glutamic acid is a peptide composed of multiple units of the amino acid glutamic acid. At low pH, such as pH 2.4, the glutamic acid residues in the peptide are protonated and carry a positive charge. At high pH, such as pH 7.5, the glutamic acid residues are deprotonated and carry a negative charge. The formation of an alpha helix in a peptide is primarily driven by hydrogen bonding between the amide groups of the peptide backbone. At low pH, the positive charges on the glutamic acid residues can interact with the negative charges on the backbone amide groups, stabilizing the helix conformation. However, at high pH, the negative charges on the glutamic acid residues repel the negative charges on the backbone amide groups, destabilizing the alpha helix conformation. Therefore, the poly glutamic acid peptide is not able to form an alpha helix at pH 7.5.”

The response the AI gave me contains several errors. These errors include incorrect facts and incorrect implications about protein structure. Analyze the response the AI gave me and identify 3 different sentences with errors in them. For each sentence that you identify you should 1. Clearly explain the nature of all the errors in the sentence, and 2. how the errors could be corrected. Note that some of the errors in the answer are implied and not directly stated. For each sentence that you identify as having an error cut and paste the sentence into your answer. Then below the AI sentence you have chosen give your answer. Your entire answer should be no longer than 1 page in length. You should not identify any simple spelling/terminology errors when answering.

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