which of the following statements about genome-wide association studies (GWAS) is correct? A) involves scanning the genomes of thousands of unrelated individuals with a particular mutation and comparing them with the genomes of individuals who do not have the mutation. B) involves scanning the genomes of thousands of unrelated individuals with a particular disease and comparing them with the genomes of individuals who do not have the disease C) attempt to identify genes that influence mutation risk D) attempt to identify genes that influence disease risk E) involves scanning the genomes of thousands of unrelated individuals with a particular disease and comparing them with the genomes of individuals who do not have the disease and GWAS attempt to identify genes that influence disease risk

Q: What is structural variation of genomes? Describe the mechanisms that create structural variants,…

A: Structural variations are referred to variation or difference in the structure of chromosome of…

Q: Discuss the sequencing technology used to resolve the human genome in 2005, its significant…

A: Sequencing used in 2005 human genome project.

Q: Why is Sanger sequencing sometimes referred to as "dye-terminator" sequencing?

A: Frederick Sanger and his colleagues created Sanger Sequencing, often known as 'chain termination…

Q: If a pair of 10-mer primers are used in a PCR, what would be the number of expected binding sites in…

A: PCR is a polymerase chain reaction, in this process DNA is amplified . For this amplification,…

Q: Why is targeting a medication like BiDil at African-Americans a flawed idea from an evolutionary…

A: The African Americans patients with congestive heart failures and issues were being prescribed with…

Q: How would you use PCR-amplified oligonucleotide directed mutagenesis to create deletion of amino…

A: Subtilisin is a protease that is obtained from bacteria Bacillus subtilis. It belongs to the group…

Q: In a genomic analysis looking for a specific disease gene, one candidate gene was found to have a…

A: Point mutations are of several kinds deletion inversion substitution duplication   The single base…

Q: When half of the DNA in the sample is double-stranded, that point is termed the half- reaction time…

A: Cot values give the renaturation index of the DNA strands. Cot 1/2 value defines that 50%…

Q: What are the benefits of using a mixture classification scheme as outlined in DNA Box 14.1? What…

A: INTRODUCTION German stain commission This commission includes several forensic science and legal…

Q: James Noonan and his colleagues (J. Noonan et al. 2005. Science 309:597–599) set out to study the…

A: Deoxyribonucleic acid (DNA) sequencing is the process of determining the nucleic acid sequence based…

Q: You want to identify and compare the gene expression profile of several genes in a disease. Will you…

A: Hi! Thank you for the questions. As you have posted multiple questions, I will be answering the…

Q: Who proposed shotgun sequencing?

A: The method used for the sequencing of random DNA strands is genetics, shotgun sequencing.  This is…

Q: What is Central Dogma of Molecular Biology?

A: The organisms that contain DNA as a genetic material shows a fascinating process within the cell is…

Q: What is the program Finch TV used for? Viewing next generation sequencing data Opening sequencing…

A: Ans- C EXPLANATION- FINCH Tv is the tool or application used by the researchers to view, analyze,…

Q: What are the components needed for the processes of transformation, conjugation, and transduction?…

A: 1.The genetic transfer in bacteria happens through three major processes.They are:…

Q: What is a transgenic organism?​   a. ​an organism that has had its entire genome sequenced   b.…

A: Deoxyribonucleic acid (DNA) is a hereditary molecule that passes genetic information from one…

Q: What is domain? And Why is it complicated to classify and study domains purely using sequence…

A: All the prokaryotic organisms belong to Archea or Bacteria while eukaryotic organisms belong to…

Q: What were the two major goals of the Human Genome Project? Select all that apply.   a to isolate…

A: Introduction :- The Human Genome Project was an international scientific research project aimed at…

Q: How does molecular biology paved way for the development of the DNA fingerprinting technique? and…

A: DNA fingerprinting was invented in 1984 by Professor Sir Alec jeffreys after he realised that…

Q: How the Sequencing Technologies Have Progressed Rapidly ? Explain about this ?

A: Early efforts at sequencing genes ere troublesome, when Gilbert and Maxam reported the sequence of…

Q: What molecular biology principle is the basis for DNA fingerprinting?

A: In this question we will discuss about the molecular biology principle basis of the DNA…

Q: With the many high throughput experiments that are used in biomedical research, how are some ways to…

A: High-throughput screening (HTS) is a method for scientific experimentation especially used in…

Q: How many different explanations can you think of for the observation that the rate of mutation…

A: A mutation is a change in our DNA sequence that happens as a result of errors in DNA copying or…

Q: Next-generation sequencing reveals that six new mutations have occurred in the coding regions of…

A: Mutations are sudden heritable changes in the genetic make up of an organism because of several…

Q: Recombinant DNA techniques are used to custom –build bacteria for two main reasons: to make a…

A: Recombinant DNA technology is a technique that genetically altered vector is introduced and…

Q: What are some possible reasons that researchers might be interested in identifying the gene that…

A: ICA(Internal Carotid Artery) is a part of the vascular system which is susceptible to Carotid artery…

Q: Fill the Table with mutagenic agents and provide their type (physical, chemical, biological) and…

A: Mutagens are the known sources of physical, chemical or biological triggers of faults through…

Q: If you had the ability to do gene editing with ONE gene for the betterment of human kind, which one…

A: Hemophilia is a hereditary problem that causes interior and outer draining by keeping blood from…

Q: Which of the following mutagens can substitute bases in DNA because of structural similarity?…

A: A mutagen is defined as any physical or chemical substance that can cause a mutation by altering an…

Q: Define all the terms we use to describe the different types of mutations. For example, true-back…

A: Mutations are changes in the DNA or RNA sequence of a particular gene that is heritable and often…

Q: In a genomic analysis looking for a specific disease gene,one candidate gene was found to have a…

A: The discovery, measurement, or comparison of genomic properties such as DNA sequence, structural…

Q: Define all the terms we use to describe the different types of mutations. For example, true-back…

A: Change in the sequence of DNA is referred to as a mutation. This change can occur because of the…

Q: What is the Central Dogma of Molecular Genetics? What impact did the discovery of RNA tumor viruses…

A: The Central Dogma was first proposed in 1958 by Francis Crick. He was also the discoverer of the…

Q: Did Hershey and Chase overcome objections to Avery et al.’s claim that DNA, not protein, was the…

A: DNA stands for deoxyribonucleic acid and is the genetic material in most of the organisms that serve…

Q: During PCR amplification in preparation for DNA sequencing, why were there different colors at the…

A: Polymerase chain reaction is a process by which millions of copies of a specific DNA segment are…

Q: What is the difference between a map-based approach to sequencing a whole genome and a whole-genome…

A: Deoxyribonucleic acid (DNA) is a double stranded helical genetic material containing thousands of…

Q: Increasingly, whole-genome sequencing of individuals is being done to help identify and treat…

A: Whole genome sequencing technique is done to sequence all the genes present in the genome of the…

Q: What is the major difference between the strategies of map based sequencing and shotgun sequencing?

A: DNA sequencing is a process in which sequence(order) of nucleotides in DNA is determined. It…

Q: What is the suitable amounts of genomic DNA to prepare PCR? and what is the suitable purities of the…

A: Ans:-Normally used concentration are 100-250 ng for mammalian genomic DNA and 20 ng for linearized…

Q: Hi, I would like to know which program is used for the graphical presentation of the results of a…

A: A genome wide linkage association study (GWAS) is an approach used in genetic research to associate…

Q: How can you tell whether DNA sequences from two sources are similar by chance or instead by common…

A: DNA or deoxyribonucleic acid is a polymer of deoxyribonucleotides connected together via…

Q: What is the primary disadvantage of Sanger sequencing?

A: Sanger sequencing the target DNA sequence is determined by copying it into the fragments of…

Q: Sequencing a genome and identifying individual genes are processes typically carried out  - A. via…

A: The DNA sequencing method is primarily developed by Gilbert and Sanger. Maxam–Gilbert's sequencing…

Q: You purified the genome of the coliphage X174. After analysis, you composition is 25 percent A, 33…

A: E. coli-infecting viruses are known as coliphages. These viruses, in addition to the conventional…

Q: What is a genome and what is it composed of? What is thecentral dogma of molecular biology?

A: Genes are the hereditary units that are transmitted from one generation to another generation. The…

Q: Explain the concept of inherited molecular disease ?

A: A condition that deteriorates the normal functioning of the cells, tissues, and organs is known as…

Q: Explain the Detection of the sickle-cell mutation by sequencing of PCR products?

A: The disorder in which a group of red blood cells becomes sickle-shaped, it is known as sickle cell…

Q: How would one recognize a gap in the genome sequence following nucleotide sequencing?

A: DNA is made up of four bases namely adenine (A), thymine (T), cytosine (C), and guanine (G). The…

Q: What it is called when two regions of the genome in different species share similarities like those…

A: Genome Genome can be defined as the the complete set of of gene of an living organism.

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.