You have an alcohol and an amine of comparable size (both 10 carbons) that you want to separate and isolate both by silica gel chromatography, either tlc or a column. Which of the following pure solvents or solvent mixtures would have the best chance of working? Remember you need to compromise-too non-polar or too polar won't work. Hexane cyclopentane with a trace of diethyl ether methanol alcohol with a little water ethyl acetate with a trace of ethanol ethyl alcohol

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
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Chapter33: High-performance Liquid Chromatography
Section: Chapter Questions
Problem 33.15QAP
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You have an alcohol and an amine of comparable size (both 10 carbons) that you want to separate and
isolate both by silica gel chromatography, either tlc or a column. Which of the following pure solvents or
solvent mixtures would have the best chance of working? Remember you need to compromise-too non-polar
or too polar won't work.
оооо
Hexane
cyclopentane with a trace of diethyl ether
methanol alcohol with a little water
ethyl acetate with a trace of ethanol
ethyl alcohol
It is not ethyl alcohol, can you please
explain your answer. Thank you.
Transcribed Image Text:You have an alcohol and an amine of comparable size (both 10 carbons) that you want to separate and isolate both by silica gel chromatography, either tlc or a column. Which of the following pure solvents or solvent mixtures would have the best chance of working? Remember you need to compromise-too non-polar or too polar won't work. оооо Hexane cyclopentane with a trace of diethyl ether methanol alcohol with a little water ethyl acetate with a trace of ethanol ethyl alcohol It is not ethyl alcohol, can you please explain your answer. Thank you.
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