Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Chapter 11, Problem 17QP
Tay-Sachs disease is an autosomal recessive disease. Affected individuals do not often survive to reproductive age. Why has Tay-Sachs persisted in humans?
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Sickle-cell disease is an autosomal recessive disorder that causes the red blood cells of an affected person to be rigid and abnormally shaped. The life expectancy of a person affected by the disorder is approximately 45 years. Carriers of the disease produce some sickled cells, but not enough to be symptomatic.Malaria is a potentially fatal disease caused by the protist Plasmodium falciparum.Studies have shown that those affected by sickle-cell disease (genotype ss), as well as carriers who possess only one sickle-cell allele (Ss), are much more resistant to malaria than those with homozygous dominant genotypes (SS). This resistance is created in part by the rupturing of any sickled red blood cells that are infected with the parasite, preventing Plasmodium falciparum from reproducing and making it more susceptible to the host's immune system.Which of the following statements best predicts what would happen in response to a prolonged epidemic of malaria in a population with no previous…
Why are recessive conditions more common than dominant ones? How could being a carrier of a recessive disease be beneficial?
Consider an autosomal recessive disease in which an individual must inherit two recessive alleles to display the disease phenotype. What is the probability that a woman who is a heterozygous for the trait and a man who is homozygous for the dominant allele will produce an offspring with the autosomal recessive phenotype? Assume no new mutations occur. Select one
1.) 100%
2.)25%
3.) 0%
4.)50%
5.) More information is needed
Chapter 11 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 11.4 - Consumer products including bandages, cotton...Ch. 11.4 - Prob. 2EGCh. 11 - Prob. 1CSCh. 11 - Prob. 2CSCh. 11 - Prob. 3CSCh. 11 - Prob. 1QPCh. 11 - Achondroplasia is an autosomal dominant form of...Ch. 11 - Why is it almost impossible to directly measure...Ch. 11 - What are the factors that influence the mutation...Ch. 11 - Achondroplasia is a rare dominant autosomal defect...
Ch. 11 - Although it is well known that X-rays cause...Ch. 11 - Prob. 7QPCh. 11 - Bruce Ames and his colleagues have pointed out...Ch. 11 - Define and compare the following types of...Ch. 11 - If the coding region of a gene (the exons)...Ch. 11 - Two types of mutations discussed in this chapter...Ch. 11 - Prob. 12QPCh. 11 - A frameshift mutation is caused by a: a....Ch. 11 - In the gene-coding sequence shown here, which of...Ch. 11 - Prob. 15QPCh. 11 - Familial retinoblastoma, a rare autosomal dominant...Ch. 11 - Tay-Sachs disease is an autosomal recessive...Ch. 11 - Replication involves a period of time during which...Ch. 11 - Our bodies are not defenseless against mutagens...Ch. 11 - The cystic fibrosis gene encodes a chloride...
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- Albinism is characterized by the lack of a dark pigment called melanin in the hair, skin and eyes. Albinism is caused by the absence of an functioning enzyme called thyrosinase, which is necessary for the synthesis of melanin. Given this bit of information, what can you assume about the heredity pattern of this trait? A) It is caused by a recessive allele of the gene coding for thyrosinase. B) It is caused by a dominant allele of the gene coding for melanin. C) It is caused by a dominant allele of the gene coding for thyrosinase. D) It is caused by a recessive allele of the gene coding for melanin. E) There is not enough information here to tellarrow_forwardThe following pedigree represents the inheritance of an autosomal recessive disease in a certain family. 2 5 2 4 5 8 3 4. 6. 1 1- How many males are affected by the disease? 3- How many children did the couple Il-4 and Il-5 have? 4- How many sisters did III-8 have? 5- What is the genotype of III-8? 40arrow_forwardWhy do scientists believe that the sickle-cell trait has not evolved out of the human population yet considering how deadly it is to be homozygous for the sickle cell gene?arrow_forward
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