Genetics: From Genes to Genomes
Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 16, Problem 45P

Scientists are currently screening a chemical library of small molecules for inhibitors of bioluminescence in response to high cell density in V. fischeri. The small molecules were chosen for their potential ability to bind LuxR.

a. How could a molecule that binds LuxR prevent bioluminescence?
b. Hundreds of different bacterial species use quorum sensing mechanisms similar to that of V. fischeriand
encode proteins similar to LuxI and LuxR. In light of this information, why do you think scientists want to
identify the molecule described in part (a)?
Blurred answer
Students have asked these similar questions
Many genetic systems use the lacZ gene encoding b-galactosidaseas a reporter. What advantages or problems would there be if(a) luciferase or (b) green fluorescent protein were used instead ofb-galactosidase as reporters?
A chain of biochemical events is responsible for Aequorea victoria turning green. Firstly, the protein aequorin converts chemical energy into blue light. A second protein, known as GFP (green fluorescent protein), absorbs the light. Aequorin is a 21 kDa protein with a pI of 4.5 that generates blue light from an attached non-protein chromophore. GFP is a 27 kDa protein with a pI of 6.2. In order for it to fluoresce, 3 amino acids undergo a remarkable reaction when they are folded in the right way. Aequorin does not absorb light in the visible range, and GFP absorbs light at 395 nm and 475 nm.  1. Sketch what you would see if you ran a mixture of aequorin and GFP over a size-exclusion column. In your sketch, include absorbance data at 280, 395, and 475 nm.
There is a group of six or so genes, called luxlux genes, whose gene products are necessary for light formation. Given that these bacterial genes are regulated together, propose a hypothesis for how the genes are organized and regulated.   Match the terms in the left column to the appropriate blanks in the sentences on the right. Terms can be used once, more than once, or not at all.   Terms: metaboliozed, density, quorum sensing, state, signal amplification, inhibit, activate, detected, secrete, transcrption initiation complex, consume, operon   Bacterial cells blank molecules that can be blank by other bacterial cells. Sensing the concentration of such signalling molecules allows bacteria to monitor the local blank of cells, a phenomenon called blank. There is a group of genes in the genome of the described bacterium, called luxgenes, which are organized in an blank. Reaching a certain concentration, molecules involved in this process blank the luxgenes. As a result, the…

Chapter 16 Solutions

Genetics: From Genes to Genomes

Ch. 16 - Mutants were isolated in which the constitutive...Ch. 16 - Suppose you have six strains of E. coli. One is...Ch. 16 - The previous problem raises some interesting...Ch. 16 - For each of the E. coli strains containing the lac...Ch. 16 - For each of the following growth conditions, what...Ch. 16 - For each of the following mutant E. coli strains,...Ch. 16 - Maltose utilization in E. coli requires the...Ch. 16 - Seven E. coli mutants were isolated. The activity...Ch. 16 - Cells containing missense mutations in the crp...Ch. 16 - Six strains of E.coli mutants 16 that had one of...Ch. 16 - a. The original constitutive operator mutations in...Ch. 16 - In an effort to determine the location of an...Ch. 16 - Prob. 23PCh. 16 - The footprinting experiment described in Fig....Ch. 16 - Why is the trp attenuation mechanism unique to...Ch. 16 - a. How many ribosomes are required at a minimum...Ch. 16 - The following is a sequence of the leader region...Ch. 16 - For each of the E. coli strains that follow,...Ch. 16 - Prob. 29PCh. 16 - For each element in the list that follows,...Ch. 16 - Among the structurally simplest riboswitches are...Ch. 16 - Great variation exists in the mechanisms by which...Ch. 16 - Many genes whose expression is turned on by DNA...Ch. 16 - In 2005, Frederick Blattner and his colleagues...Ch. 16 - The E.coli MalT protein is a positive regulator of...Ch. 16 - Prob. 36PCh. 16 - Prob. 37PCh. 16 - Prob. 38PCh. 16 - Prob. 39PCh. 16 - Prob. 40PCh. 16 - Prob. 41PCh. 16 - The researchers who investigated bioluminescence...Ch. 16 - Prob. 43PCh. 16 - Quorum sensing controls the expression of...Ch. 16 - Scientists are currently screening a chemical...
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
genetic recombination strategies of bacteria CONJUGATION, TRANSDUCTION AND TRANSFORMATION; Author: Scientist Cindy;https://www.youtube.com/watch?v=_Va8FZJEl9A;License: Standard youtube license