The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity. Introduction : Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

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Answer 1

Question

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

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Answer 2

Question

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

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Answer 3

Question

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

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Answer 4

Question

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

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Answer 5

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

Answer 6

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

Answer 7

Chapter 17, Problem 11P

Summary Introduction

To determine: The changes in metabolic pattern that would result from mutation in the muscle carnitine acyltransferase-1 in which the mutant protein has lost its affinity for malonyl-CoA but not its catalytic activity.

Introduction:

Shuttle system having intermediate fatty acyl-carnitine is needed to transport molecules of fatty acid into mitochondria. Before transportation of fatty acid molecules, fatty acids are first transformed into fatty-acyl coenzyme A in the cytoplasm which is done by acyl-CoA synthetase. After that fatty acyl groups are transported to carnitine present at the outer mitochondrial membrane by carnitine acyltransferase-1 enzyme.

Answer 8

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Answer 9

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Answer 11

Ch. 17 - Prob. 1P Ch. 17 - Prob. 2P Ch. 17 - Prob. 3P Ch. 17 - Prob. 4P Ch. 17 - Prob. 5P Ch. 17 - Prob. 6P Ch. 17 - Prob. 7P Ch. 17 - Prob. 8P Ch. 17 - Prob. 9P Ch. 17 - Prob. 10P

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