Microbiology: An Introduction (13th Edition)
Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Chapter 19, Problem 1R

DRAW IT Label IgE, antigen, and mast cell, and add an antihistamine to the following figure. What type of cell is this? Singulair stops inflammation by blocking leukotriene receptors. Add this action to the figure.

Chapter 19, Problem 1R, DRAW IT Label IgE, antigen, and mast cell, and add an antihistamine to the following figure. What

Expert Solution & Answer
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Summary Introduction

To determine:

The inflammation of singuliar blocks by blocking leukotriene’s receptors.

Introduction:

Type 1 hypersensitivity can cause immune response to the exposure of antigens. When IgE antibodies bind to the receptors on mast cells, then they will bind to the antigen. It causes degranulation of mast cells and the release of granules like histamine and leukotrienes. It leads to inflammation and breathing difficulties. This is blocked by giving singuliar drug.

Answer to Problem 1R

Correct answer:

A mast cell is given in this figure. An antihistamine is added to the mast cell; it blocks the inflammation.

Explanation of Solution

Diagram:

Microbiology: An Introduction (13th Edition), Chapter 19, Problem 1R , additional homework tip  1

Leukotrienes attach to the receptors of mast cells; they cause inflammation. When a leukotriene receptor is blocked by singuliar, it stops inflammation. Mast cells play a role in autoimmune disorders. Singuliar (Montelukost) relieve the symptoms of hay fever, asthma, inflammation, and redness in skin. Singuliar mimics as leukotriene receptors.

Microbiology: An Introduction (13th Edition), Chapter 19, Problem 1R , additional homework tip  2

Conclusion

Anaphylactic hypersensitivity mast cell releases histamine, leukotriene, and other mediators when it binds to the antigen and IgE antibody. When leukotriene receptors are blocked by singuliar, an allergic response does not occur.

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