Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 25, Problem 18CONQ
What is a prion? Explain how a prion relies on normal cellular proteins to cause a disease such as mad cow disease.
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Which statement among A-D is false regarding bacterial toxins?
A) O Hemolysıns are cell membrane disrupters that can rupture red blood cells.
B) O Second mesengar pathway disrupters like cholera toxin produces a debilitating respiratory condition of the lungs.
C) O Shiga toxin, tetanus toxin, and hemolysins are all types of exotoxins.
D) O Superantigens elicit a hyperactive response by the immune system and can lead to shock.
E) O None are false, A-D are all true statements.
Define meningitis.Compare and contrast between bacterial and viral meningitis including treatment for each.
What is a prion? Describe the impact prionshave on the human brain and discuss two prion-associated diseases in humans:
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Can the below be added to the answer:
Some common cytopathic effects include:
Cell rounding and detachment: The infected cells may become rounded and detach from the underlying surface, leading to cell death and tissue damage.
Cell lysis: In lytic infections, the virus utilizes the host cell's resources to produce new virus particles. As a result, the infected cell eventually bursts (lysis), releasing the newly formed viruses, which can go on to infect neighboring cells.
Formation of inclusion bodies: Some viruses induce the formation of distinct structures called inclusion bodies within the infected cells. These inclusion bodies are often aggregates of viral proteins or nucleic acids and can be visualized under a microscope.
Cell fusion: Certain viruses have the ability to cause infected cells to fuse together, forming multinucleated giant cells. This fusion enhances viral spread and can lead to the destruction of affected tissues.
Cellular damage and functional impairment: Viral…
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
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- Diagrammatically explain the mechanism of cellular injury caused by virus and bacteria?arrow_forwardMost antiviral drugs: a) damage the cell wall b) are nucleoside analogs c) are enzymes inhibitors d) prevent viruses from entering cells e) damage the plasma membranearrow_forwardIntroduction: There’s quite a bit of interest around repurposing extant drugs to treat infections by targeting host pathways that pathogens rely on. Here are a few potential drugs: 1) A drug that inhibits endocytosis, but not phagocytosis. 2) A drug that inhibits degradation of cytoplasmic proteins into smaller peptides, preventing their cycling back into amino acids. 3) A drug used to treat porphyria that reduces the reactivity of heme. 4) A drug that depletes glutathione, a chemical which protects red blood cells against the reactivity of heme. 5) A drug that reduces expression of the ACE-2 protein. Question: Pick a drug and an infection that the drug is likely to be good at treating, or pick an infection and a drug that would most likely make the infection substantially worse. Which drug and pathogen did you pick? Do you think it’ll make it better or worse?arrow_forward
- A patient is admitted to the hospital with a viral infection and is immediately treated with broad-spectrum antibiotics. How will the course of the infection be affected by this treatment? The infection's length will remain the same because viruses do not have DNA or RNA, and so antibiotics do not affect them. The infection's length will be shorter because antibiotics can prevent viral entry into the cell by binding to host-receptor proteins. The infection's length will remain the same because antibiotics have no effect on eukaryotic cells or viruses. The infection's length will be shorter because antibiotics activate the immune system, and this decreases the severity of the infection.arrow_forwardWhich example would benefit most from the use of pluripotent stem cells made from the patient's own cells? A) An autoimmune disease, inappropriate targeting of the patient's immune system, destroyed a patient's thyroid gland B) A neurodegenerative disease, abnormal cell death of brain cells, destroyed a specific region of the patient's brain C) A patient suffered severe burns over much of their legs and feet D) A person with a congenital disease has been blind from birth.arrow_forwardExplain what a lysogen is.arrow_forward
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