Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
7th Edition
ISBN: 9781464126116
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 3, Problem 13P
Summary Introduction

To determine: The amino acid residues that must be present in relatively large numbers in histones.

Introduction:

Histones are alkaline proteins present in eukaryotic chromosomes. They are positively charged and bind to the negatively charged DNA (deoxyribonucleic acid). Thus, histones can be considered as the chief component of chromatin.

Summary Introduction

To determine: The ways through which amino acid residues contribute to strong binding of histones to DNA.

Introduction:

Amino acids are the monomer units of proteins. These are basically organic compounds consisting of a carboxylic group (-COOH-) and an amino group (-NH2). Along with these functional groups, a side chain (R group) is also present in all the amino acids.

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