Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
7th Edition
ISBN: 9781464126116
Author: David L. Nelson, Michael M. Cox
Publisher: W. H. Freeman
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Chapter 7, Problem 3P
Summary Introduction

To explain: The reason that why does glucose and mannose, and similarly galactose and talose, form osazone derivatives with the same melting points.

Introduction:

Osazone is a derivation of carbohydrate studied in organic chemistry. This osazone formed when carbohydrate or sugar groups react with excess amount of phenylhydrazine. This osazone is developed by German chemist name Emil Fischer to identify the epimers of carbohydrate.

Given:

Tabular representation: Table 1 represents the melting points of some aldose-osazone derivatives.

Monosaccharide Melting point of anhydrous monosaccharide (°C) Melting point of osazone derivative (°C)
Glucose 146 205
Mannose 132 205
Galactose 165-168 201
Talose 128-130 201

Table 1: Melting points of aldose-osazone derivatives.

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