Developmental biology

unlike embryonic stem cells that grow into any type of mature cell, adult stem cells can only grow into certain cell types. Now, researchers from Harvard-affiliated Brigham and Women’s Hospital (BWH), in collaboration with the RIKEN Center for Developmental Biology in Japan, have demonstrated that any mature adult cell (a “somatic” cell) has the potential to turn into the equivalent of an embryonic stem cell. In an article to be published in the Jan. 30 issue of Nature, researchers demonstrate, in a preclinical

Targeted genome-editing technology is an area of great attention for biomedical research fields, as it has potential in clinical applications to cure or improve some genetic diseases. In particular, the case of genome manipulation has been revolutionized by the development of the CRISPR/Cas 9 system. Despite recent advances in editing targeted genes inside of cultured cells, in vivo targeted transgene integrations are still out of reach, because of current tools. Principally, this applies to nondividing

Advancements in medical technology has allowed for a new understanding of stem cells and further developments in research. The use of stem cells in regenerative medicine may hold significant benefits for those suffering from degenerative diseases. To avail such advancements in stem cell research could see the alleviation or complete cure of afflictions that take the lives of millions worldwide each year. (McLaren, 2001) A stem cell 1 is able differentiate into any somatic cell found in the human

Over the past decade, stem cell biology has been an area that has caused much controversy. Stem cells have the ability to differentiate into many different types of cells and therefore, advocates of stem cell research argue that the cells have various medical applications. On the other hand, opponents of stem cell research denounce the use of human embryos for research purposes, claiming that the embryos represent human lives and that experimentation with them and subsequent annihilation of them

Erika Ramos Mrs. DeCarvalho English 10 13 April 2015 The Benefits of Stem Cells Stem cell research holds the cures and treatments for most of the major diseases in the world. Many people with major and deadly diseases may be benefited by stem cell research. Other people have been fortunate enough to have had the benefits of it already. There are two types of cells, which are embryonic and adult stem cells. Embryonic stem cells can become any type of cell, for example, blood, brain tissue, and skin

There are many possible uses for stem cells in medical research, including developing an understanding of how diseases and conditions develop by observing how stem cells mature from a fertilised egg into specialised cells, otherwise known as developmental biology, and can be used to produce healthy cells, which can then replace diseased or damaged cells. Stem cells have already been used to replace cells damaged by diseases or chemotherapy, or in bone marrow transplants to help fight blood-related diseases

The Role of the EGF Receptor LET-23 on Lipid Biosynthesis in Caenorhabditis elegans N. R. Contos Thesis Abstract The Caenorhabditis elegans LET-23, which is an Epidermal Growth Factor (EGF) receptor, controls multiple developmental pathways. In humans, EGF receptor mutations are implicated in a large number of cancers due to excess signaling promoting cell growth and cell division. Recent work has shown that in C. elegans LET-23 may also affect lipid production, specifically that of the phospholipid

Researchers have been conducting studies that could bring us closer to a breakthrough in regenerative medicine. Scientifically, regeneration means the process of regrowth of damaged or lost tissue. When the human body has become fully matured, around the age twenty-five human organs, such as the liver can be regenerated. If any damage is caused to the liver it is capable of regenerating itself, although it may not fully return to its original state. Our skin can also be classified as undergoing regeneration

A Somitic Compartment of Tendon Progenitors Summary Tendons are some of the most important tissues in the body of any organism, transferring the power created by the muscles to the bones and allowing coordinated body movements to occur. However, until recently there was very little known about the origin of this tissue and most of the research performed focused on the limbs and the tendons associated with them. Along with the limited amount of research seemingly none of it was focused on the axial

Alyssa Gbewonyo Biology 441 Section 16138 December 11, 2014 Induced Pluripotent Stem Cells—Derived Neural Crest Stem Cells and the maintenance of Neural crest stem cell multipotency Stem cells are unspecialized cells, which have the potential to develop into several different cell types—muscle cells, brain cells, skin cells, or red blood cells—during early development. Stem cells continuously divide in order to replace other cells. As stem