Glycoprotein

Dwayne Hill. BC34M November 30, 2007 Lab Partner: Sasha-Kaye Graham Experiment 6 : Lectin Agglutination Aim: To study the agglutination pattern of different strains of Psuedomonas aeruginosa to different sialic acid-binding lectins. Absract: The cell membrane of two strains of Psuedomonas aeruginosa, P22 and P201 were treated the sialic acid lectins SNA I, WGA, MAL and HAA to confirm the presence of sialic acid carbohydrates in the cell surface membranes of these strains. This was done by

P-glycoprotein Inhibitor Improvement: Verapamil There are plenty of drugs that are targeting P-glycoprotein (p-gp), which is typically located in intestinal epithelial cells where drugs absorption occurring. The p-gp controls in and out of most of foreign substrates from the blood stream. It contributes to balancing out the concentration of drugs in the blood vain through reuptake process, especially efflux pump in this case. Therefore, this protein has been called as multidrug resistance because

developing small molecules to decrease drug resistance in cancer cells. This resistance greatly decreases the effectiveness of many drugs and poses a challenge in treating different types and cancer. Specifically, we focused on reversibly inhibiting P-glycoprotein (P-gp), an ATP-dependent transporter that enhances multidrug resistance along the plasma membrane of many cancer cells, and the capillary lining of the blood brain barrier. The normal function of P-gp is to efflux xenobiotics, preventing the accumulation

Figure 1: This figure shows the dystrophin–glycoprotein complex network. What’s shown in red makes up the core dystrophin-glycoprotein complex and are not found as abundantly in dystrophin deficient muscle. What’s shown in blue are proteins that are more abundant when there are low dystrophin levels. The white shows structural proteins that directly interact with the dystrophin-glycoprotein complex. (16) Muscle tissues will weaken progressively and can eventually this disease usually leaves victims

This issue could further be addressed by using radial as opposed to femoral access when carrying out pPCI. A trial found that there was a reduced incidence of major bleeding and vascular site complication with a radial approach. Events occurring in 1.4% of those treated with radial approach and 7.2% P<0.0001 of those with femoral access with a reduction in the rate of net adverse clinical events (NACE) defined as “a composite of death, myocardial infarction, stroke, and major bleeding/vascular complications”

hemostasis, platelet aggregation and/or coagulation. 3 Eptifibatide is a cyclic heptapeptide which originated from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarus barbouri) and selectively blocks the platelet glycoprotein IIb/IIIa receptor. It belongs to the class of the so called arginin-glycin-aspartat-mimetics and reversibly binds to

against both hendra and nipah virus shows effective inhibition of hendra and nipah virus. The henipavirus have two envelope proteins F & G glycoproteins; the G glycoprotein is an attachment glycoprotein while F is the fusion glycoprotein. The recent tactic to prevent henipavirus infection focused on direct medication by soluble forms of F & G viral glycoproteins to induce a protective immune response. INTRODUCTION Hendra virus (HeV) and Nipah virus (NiV) from genus henipa virus are zoonotic

P-glycoprotein lowers the intracellular concentration of tacrolimus by pumping the absorbed tacrolimus back out into the intestinal lumen, it is repeatedly transported out of the intestinal mucosa cells and then passively reabsorbed. This extensive presystemic

platelets, which result in easy bruising and nosebleeds, and was first described in 1918. Glanzmanns disease is a congenital hemorrhagic disorder, meaning it's a bleeding disorder present at birth. Glanzmanns disease results from not having enough glycoprotein, a protein usually found on the surface of blood platelets. Platelets are small blood cells that are the first responders in the case of a cut or injury, they normally clump together to form a plug in the wound and stopped bleeding. Glanzmanns

Cold Sore Frenzy Fran’kita Wiggins Dr. Shen Virology Virginia State University There are eight herpes viruses that infect humans. Many of the herpes viruses are neurotropic meaning that they infect the nervous tissue. These viruses are termed alpha-herpes viruses. All herpes viruses have similar structure. They all have icosahedron envelope, the matrix and the capsid. The virus seems to replicate the immune defense of its host to insure successful replication. All the herpes viruses share