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Characteristics Of Malignant Hyperthermia ( Mh )

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Abstract
Malignant Hyperthermia (MH) is a genetically inherited, pharmacogenic disorder involving a severe malfunction within the skeletal muscles, causing them to be stuck in a contracted state. It is found to be triggered in susceptible patients by the administration of certain anesthetic agents during and after surgical procedures. It may also be activated by the use of other drugs, such as muscle relaxants and triggered by other circumstances such as stress, trauma, and even exercising. Not only are the muscles normal physiology affected, but abnormalities of the whole body occur disrupting its natural homeostasis. If it is not treated immediately, it can be fatal. Susceptibility is found in patients who have had a known family history of MH. In order for a medical professional or a patient to be prepared to handle MH one must understand how it affects the normal physiology of the body, what signs to look for, and how it can be diagnosed, treated, and prevented. There is no cure for MH, but there are specific drugs and precautionary measures that are used to prevent and treat it when a patient is susceptible.

A Brief Overview of Malignant Hyperthermia
Malignant Hyperthermia is a life-threatening, genetic disorder that involves the skeletal muscles. It commonly occurs intraoperatively and postoperatively when inhalant agents such as halothane, enflurane, and isoflurane are used, as well as some muscle relaxants such as succinylcholine and curare. It

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