Essay on Diabetes Mellitus

Negative feedback caused the changes in plasma insulin because when the body doesn't produce enough insulin it takes glucose from the

If the blood glucose level falls to dangerous levels, the alpha cells of the pancreas release glucagon. This hormone has effects on the liver cells that increase blood glucose levels. They convert glycogen into glucose (glycogenolysis). The glucose is released into the bloodstream, increasing blood sugar levels. Hypoglycemia, the state of having low blood sugar, is treated by restoring the blood glucose level to normal by the ingestion or administration of dextrose or carbohydrate foods. In more severe circumstances, it is treated by injection or infusion of

Type 2 is characterized by the body’s inability to use insulin effectively because of a combination of resistance to insulin as well as an overall decrease production in insulin. There is a genetic predisposition to Type 2 diabetes, but there are several other factors that also put an individual at

Sugar is the primary fuel for the cells in the body, and the insulin takes the sugar from the blood and into the cells. When glucose builds

     Diabetes mellitus is a group of metabolic disorders characterized by inadequate insulin secretion by the pancreas or cellular destruction leading to an insulin deficiency. Depending on the cause of the insulin shortage, diabetes can be subcategorized into type I and type II. Type I diabetes (T1DM) is usually mediated by the destruction of b-cells in the pancreas resulting in decreased insulin production and secretion. Type II diabetes (T2DM) is the failure of these b-cells to secrete adequate amounts of insulin to compensate for insulin resistance and increased gluconeogenesis combined with an overall resistance to the insulin action (8., 1997). T2DM accounts

Insulin resistance is the first physiological change occurring in type two diabetes. In these type two diabetic patients, insulin is unable to move glucose into liver, kidney and muscle cells although insulin is able to attach properly to the cell surface receptors. In order to rectify this, most patients with type two diabetes start secreting normal to very high levels of insulin, which can initially overcome this resistance. After a while, the pancreas cannot keep up with this high insulin production and the cells become resistant to glucose intake. Persistent hyperglycemia or high blood glucose levels are not desirable since this causes damage to the beta cells of the pancreas that produces the insulin hormone. This damage to beta cells further hampers insulin synthesis and patients at this stage are categorized as full-blown diabetic. Such patients consistently show a hyperglycemia state even after hours of fasting ( Hinkle & Cheever,

He said, diabetes mellitus is a chronic disease that occurs when the body doesn 't make enough of insulin, or the body doesn 't use insulin properly. Insulin is a key to regulation of blood glucose in our body. In types II diabetes a condition of when insulin insensitivity as a result of insulin resistance that decreases insulin production and eventual pancreatic beta-cell failure enough insulin to meet body needs. Impairment of beta- cell also can lead to problems with insulin production and resistance that can interfere with the process of glucose uptake in by cells and muscle. This condition leads to a decrease in glucose transport into the liver, muscle cells, and fat cells which can lead to a condition called hyperglycemia. Hyperglycemia occurs when there is a high level of blood glucose levels in our blood (Concepts Advisory Panel (2015) p.742).

Diabetes Mellitus is a disorder characterized by an imbalance between insulin production, insulin need, and the bodies ability to use the available insulin. This imbalance can result from a total lack of insulin, from impaired release of insulin, inadequate or defective insulin receptors in body tissue, or from the production of insulin that is either inactive or destroyed before it can become effective.

Unlike type 1 diabetics, type two diabetics acquire the disorder over time. Insulin resistance prevents the cells from reacting to the

either resists the effect of insulin in the body or doesn’t produce enough insulin to

Special cells called beta cells located in the pancreas produce a hormone called insulin. The function of insulin is to transform blood sugar, also known as glucose, taken from foods consumed into energy. Insulin moves glucose into cells where it is stored for energy use. Type-two diabetes occurs when the body is incapable of utilizing insulin properly due to the failure of appropriate production from the pancreas. This failure, called insulin resistance, inhibits blood sugar from entering the cells throughout the body and turning it into energy. The glucose is not able to enter the cells, thus creating high levels of sugar in the blood. This elevated sugar levels in the blood is also known as hyperglycemia. In an overweight or obese body, it is harder to utilize insulin correctly due to the increased body fat. Although a normal weight person can develop diabetes, the chances are greater with increased fat in the midsection of the body. A malfunctioning liver, miscommunication between cells, and damaged beta cells could also lead to diabetes. Factors

Diabetes mellitus (DM) is a condition in the body that is related to a faulty metabolism. It means that the body’s metabolism is not functioning properly, which leads to adverse effects in the health. The food we ingest, gets broken down into blood sugar (glucose), which is what fuels our body in the form of energy. This converted glucose needs to enter our cells so that it can be used for energy and growth. And in order for the glucose to enter our cells, there needs to be insulin present, which the beta cells of the pancreas is responsible for producing. This hormone is responsible for maintaining glucose level in the blood. It allows the body cells to use glucose as a main

For this reason, type 1 is also recognized as insulin dependent diabetes mellitus. Type 1 diabetes is not as common as type 2 diabetes. According to MNT only 10% of diagnosed diabetes cases are type 1 diabetes. In type one diabetes the pancreatic beta cells have been destroyed by the immune system and there is no production of insulin. As the body is not able to produce insulin an external supply of insulin hormone must be prescribed. Insulin is commonly given via injection to control the high levels of glucose in the blood. High levels of blood are referred as to hyperglycemia.

Diabetes mellitus (sometimes called "sugar diabetes") is a condition that occurs when the body can 't use glucose (a type of sugar) normally. Glucose is the main source of energy for the body 's cells. The levels of glucose in the blood are controlled by a hormone called insulin, which is made by the pancreas. Insulin helps glucose enter the cells.

     Diabetes is a chronic condition in which the body produces too little insulin (Type One Diabetes) or can’t use available insulin efficiently ( Type Two Diabetes). Insulin is a hormone vital to helping the body use digested food for growth and energy.