A modification is made in the Gas (G alpha s) signaling pathway by the process of evolution. This modification results in negat feedback within the Gas pathway. Which of the following modifications would result in negative feedback that would attenuat (decrease) the resulting signal while the ligand activating the pathway is present? O A. The G-protein coupled receptor that activates Gas is endocytosed and degraded. O B. A target gene is transcribed that encodes for phosphodiesterase. O C. Adenylyl cyclase activates PKA D. Active PKA inhibits adenylyl cyclase.

Human Heredity: Principles and Issues (MindTap Course List)
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Chapter10: From Proteins To Phenotypes
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Problem 21QP: Transcriptional regulators are proteins that bind to promoters (the 5-flanking regions of genes) to...
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A modification is made in the Gas (G alpha s) signaling pathway by the process of evolution. This modification results in negative
feedback within the Gas pathway. Which of the following modifications would result in negative feedback that would attenuate
(decrease) the resulting signal while the ligand activating the pathway is present?
A. The G-protein coupled receptor that activates Gas is endocytosed and degraded.
B. A target gene is transcribed that encodes for phosphodiesterase.
C. Adenylyl cyclase activates PKA
O D. Active PKA inhibits adenylyl cyclase.
Transcribed Image Text:A modification is made in the Gas (G alpha s) signaling pathway by the process of evolution. This modification results in negative feedback within the Gas pathway. Which of the following modifications would result in negative feedback that would attenuate (decrease) the resulting signal while the ligand activating the pathway is present? A. The G-protein coupled receptor that activates Gas is endocytosed and degraded. B. A target gene is transcribed that encodes for phosphodiesterase. C. Adenylyl cyclase activates PKA O D. Active PKA inhibits adenylyl cyclase.
Histone acetyltransferases act to unwind cis-regulatory DNA sequences from histones inside the nucleus. In general, it can
be said that histone acetyltransferases can:
O A. allows transcriptional regulators easier access to the DNA, leading to gene phosphorylation.
B. allows transcriptional regulators easier access to the DNA, leading to changes in gene expression.
O C. hinders transcriptional regulator access to the DNA, leading to gene phosphorylation.
O D. hinders transcriptional regulator access to the DNA, leading to changes in gene expression.
Transcribed Image Text:Histone acetyltransferases act to unwind cis-regulatory DNA sequences from histones inside the nucleus. In general, it can be said that histone acetyltransferases can: O A. allows transcriptional regulators easier access to the DNA, leading to gene phosphorylation. B. allows transcriptional regulators easier access to the DNA, leading to changes in gene expression. O C. hinders transcriptional regulator access to the DNA, leading to gene phosphorylation. O D. hinders transcriptional regulator access to the DNA, leading to changes in gene expression.
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