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- Discuss the suitability of bromocresol green and thymol blue (2nd change only) for use as indicators in an acetic acid - sodium hydroxide titration. Paragraph в I A + v ...Both the physical properties of the API and the excipients are essential to ensure that the formulation is physically stable and suitable for administration to patients. Discuss the general formulation considerations. The instability of emulsions may be either reversible or irreversible. Cracking indicates the extensive coalescence of the internal phase, consequently, leads to the separation of the emulsion into two distinct layers. How the cracking is occurring in the emulsions? If an emulsion has cracked will it be recovered. If yes/no discuss the phenomena. Discuss the lyophilization and appraise its importance in the pharmaceutical industry with suitable examplesYou are asked to compound maldroxyl 60 mL, diphenhydramine elixir 60 mL, and viscouslidocaine 2%, qs to 200 mL. How much viscous lidocaine 2% will you need to prepare the order?
- Prepare one dose of 0.6 mg kanamycin in 2mL diluted from a stock solution of 20 mg/ml. How much kanamycin and how much diluent are used?The usual dose for Chlorambucil is 150mcg/kg of body weight. How many milligrams should be administered to a person weighing 154lbs?Ciclosporin has been prescribed to treat a patient with severe rheumatoid arthritis. The oral dose is 2.5 mg/kg daily in two divided doses. The patient weighs 68 kg. What dose is required.
- An amino acid mixture consisting of lysine, leucine, and glutamic acid is to be separated by ion-exchange chromatography, using a cationexchange resin at pH 3.5, with the eluting buffer at the same pH. Which of these amino acids will be eluted from the column first? Will any other treatment be needed to elute one of these amino acids from the column?A patient is ordered to take 160 mg of tegretol daily for 30 days. The supply on hand is carbamazepine 100 mg/5 mL. How many milliliters should the patient receive per dose?.Your patient is order to take Theophylline 80 mg by mouth this AM. The drug label reads Theophylline 80 mg/5 mL. 1) How many mL will you prepare? 2) How many teaspoons is this?
- Give the pharmacological property of the following alkaloids. Where do they naturally occur? morphine quinine berberine What are the chemical tests used in identifying alkaloids?NEORAL oral solution contains 100 mg/mL of cyclosporine. If a pharmacist prepares 30 mL of an oral solution containing 10% w/v cyclosporine, how many milliliters of diluent should be used?From a 50% solution of dextrose, make 500 ml of a 5% solution