There are many studies related to diabetes, but it necessary to research further those studies that focus on how race/genetic factor affects diabetes. The most common focus of many studies has been to consider to further research the relationship between B-cells and diabetes. It is also believed that type two diabetes may have been associated with some genetic factors of a specific race. It is mentioned that although it is rare, in some forms of diabetes mutations of one gene can cause the disease (Dean& McEntyre, 2004.). The idea is that there are many variations in genes sequencing, which makes it difficult to link the gene variations known as single nucleotide polymorphisms (SNPs) to the risk of developing diabetes. With that said, …show more content…
During the study, 20 islets were studied from each case, and the focus was to measure B-cell volume, frequency, replication, and the ability for the endocrine ducts to produce new islet (Butler, et al. 2003). Based on the findings, there was an increase of B-cell in the obese population. “Obese humans with IFG and type 2 diabetes had a 40% (P < 0.05) and 63% (P < 0.01) deficit and lean cases of type 2 diabetes had a 41% deficit (P < 0.05) in relative β-cell volume compared with nondiabetic obese and lean cases, respectively” (Butler, et al. 2003).
Another article related to the gene theory titled Genetic and Environmental Factors Associated with type two Diabetes and Diabetic Vascular Complications conducted in 2012 by Murea, MA, and Freedman. This study focused on exploring secondary data to find what researchers have found about the relationship between genes and diabetes, and environmental factors and diabetes. This study focused more on type two diabetes and how it relates to vascular complications. It concentrates on how finding the relationship between genes and diabetic can help finding treatment option for the disease prevention or delay in the disease progression (Murea & Freedman, 2012). The authors also review and article that reviewed the literature supporting genetic determinants in the
There are several factors, however, that can increase a person's risk of developing type 2 diabetes. Primary concern and cause of type 2 diabetes is obesity or overweight, people over the normal weight baseline of the BMI spectrum. America has always been known as the country that is two/thirds obese and many of American habits contribute to the following daily bad decisions that seem related to type 2 diabetes. Poor eating habits are the number one cause of obesity and type 2 diabetes, choosing to eat bad food and lots of soda can have tremendous effects on your weight and glucose intake. Watching too much television (T.V.) is another related issue towards diabetes, most likely eating snacks while watching your favorite show or movies. Physical inactivity causes the body to have a high blood glucose causing diabetes; muscles use the glucose through physical activity by helping the hormone insulin absorb glucose into all your body cells. Your muscles use glucose better than it uses fat. Sleeping habits such as sleeping less than 5 hours or more than 9 hours a night can affect the body’s balance of insulin and increase the demand on the pancreas to make it. Lastly, genetics has played a big role in determining if a person is at risk for type 2 diabetes. Your risk is higher if your brother, sister, or parent have type 2 diabetes. Genetics is a factor that is out of our control and it is
Diabetes is a complex disease which bonds together evolution and environmental factors and creates many health issues for humans. Diabetes (mellitus) is classified into three groups of metabolic diseases that involves high blood sugar (glucose) and it can occur in different ways depending on circumstances. Type 2 diabetes occurs when cells do not function correctly, and evidently the cells do not properly respond to insulin. Type 1 diabetes involves the body’s inadequate production of insulin, which is commonly referred to as insulin-dependent diabetes. What are the links between evolution, the environment and a staggering number of people diagnosed with diabetes?
Accompanying genetics, environmental factors, such as lack of exercise and obesity, play major roles in causing type II diabetes.
(2012) suggest that, “genetic ancestry has a significant association with type 2 diabetes above and beyond its association with non-genetic risk factors for type 2 diabetes in African Americans, but no single gene with a major effect is sufficient to explain a large portion of the observed population difference in risk of diabetes. and that there is a interplay among specific genetic factors, which may both be associated with overall admixture, leading to the observed ethnic differences in diabetes
What were some of the economic and political motivations that lead to the idea of race and racial genetic differences?
The proband’s family history consist of both type 1 and type 2 diabetes; especially the females within her maternal linage. Family histories where type 1 and type 2 diabetes co-occur happens often (Nogueira, 2013). Both types of diabetes are caused by a loss of physical or functional beta cell mass (Nogueira, 2013). Type 1 diabetes (T1D) is due to an autoimmune process and type 2 diabetes (T2D)
The increase in the prevalence of type 2 diabetes is causing huge health problem through out the world including developed countries. Mostly people with low income groups are affected in developed countries (Zimmet 2001).The magnitude of the healthcare problem of type 2 diabetes results mainly from its association with obesity and cardiovascular risk factors. Indeed, type 2 diabetes has now been identified as one manifestation of the “metabolic syndrome”, a condition characterised by insulin resistance and associated with a range of cardiovascular factors (Jonathan 2003)
As a black girl, I have thought about race a lot. I have personally seen how race has affected my education, opportunities, dealings with police, employment, and everyday interactions with people. Of course, I know that race does not exist as a scientific category. The theory of race is not a biological reality, and has been proven as illegitimate.There is after all only one race - the human race. We all have the same basic characteristics and genetically are all homo sapien sapiens. Our physical differences can be explained by means of Charles Darwin’s concept of human variation. Thus, our various physical characteristics such as skin colour and hair texture are a result of our ancestors geographical origins. In contrast to its biological
The question that seems to be an ongoing topic of discussions is whether or not biological differences has any scientific validity when relating to race. The concept of race was established over the years based on physical features and variations of skin tone. These variations stem from environmental conditions causing slight variations in our genome. The essence of Homo sapiens is the same with slight variations in the DNA strands know as alleles. These variations are what cause physical differences that make up what we have defined over the years classified as different races. The variations have not evolved enough to prevent reproduction amongst the races.
An overview of the proposed sequences of the key pathological features of type 2 diabetes is provided by Dr. Jack Leahy from the University of Vermont College Of Medicine. In his article he addresses the need for continued genetic research since little discovery has been made in this area. He also explains the known environmental causes such as sedentary lifestyles and high fat diets that contribute to type 2 diabetes, changes in lifestyle practices would reduce the incidence of this disease but this is not a practical solution. The best solution according to Dr. Leahy lays in understanding the
Insulin resistance is the first physiological change occurring in type two diabetes. In these type two diabetic patients, insulin is unable to move glucose into liver, kidney and muscle cells although insulin is able to attach properly to the cell surface receptors. In order to rectify this, most patients with type two diabetes start secreting normal to very high levels of insulin, which can initially overcome this resistance. After a while, the pancreas cannot keep up with this high insulin production and the cells become resistant to glucose intake. Persistent hyperglycemia or high blood glucose levels are not desirable since this causes damage to the beta cells of the pancreas that produces the insulin hormone. This damage to beta cells further hampers insulin synthesis and patients at this stage are categorized as full-blown diabetic. Such patients consistently show a hyperglycemia state even after hours of fasting ( Hinkle & Cheever,
I never really thought about of diabetes as being a health problem in my life until I diagnosed with it. My physician told me one of the risk factor for getting diabetes is family history. My family history has big impact on to been diagnosed with types II diseases. Having one of family members have been diagnoses with diabetes mellitus increase the chance to get the disease than those not have family history. He also mention that race/ethnicity also another risk factor to develop diabetes. Also, been African Americana descent played major roles to be diagnosed
Race, such a subjective matter that most classify solely on observable traits based on traditional race concepts. However race exists in humans through cultural and biological concepts. In other words, race is based on its scientific meaning, which is taken from its visual and genetic signs of human variety. “After all it is an idea with a measurable past, identifiable present, and uncertain future”. St. A SHORT HISTORY OF THE RACE CONCEPT Michael Yudell, PhD, MPH. Through observing the human genome project that explores human molecular selves, skin color variation, and lastly race/human variation as a whole, a clear picture of race can be scientifically explained.
Type 2 diabetic patients have a stronger connection in having heredity as the cause of the illness even though it can still be caused by other factors. However, if the patient has a history of family members who have had the condition it can be challenging to determine if the diabetes was caused by genetics or other risk factors (American Diabetes Association 2016).
It more commonly affects the adults, especially elderly. Type 2 diabetes is also determined by several different genes. Many patients with type 2 diabetes have the family history of diabetes mellitus. Maternal history also plays a major role in the prevalence of the disease. The main issue is the sensitivity of the peripheral tissues decreases to the circulating insulin which is also called as insulin resistance.