Evolutionary Analysis (5th Edition)
5th Edition
ISBN: 9780321616678
Author: Jon C. Herron, Scott Freeman
Publisher: PEARSON
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Chapter 5, Problem 15Q
Suppose a silent mutation occurs in an exon that is part of the gene for TAS2R38 in a human. Has a new allele been created? Defend your answer.
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Chapter 5 Solutions
Evolutionary Analysis (5th Edition)
Ch. 5 - What is the difference between genetic variation,...Ch. 5 - We noted on the first page of the chapter that...Ch. 5 - Because you are studying different subjects, the...Ch. 5 - What are reaction norms, and why do they matter?...Ch. 5 - Consider the nucleotide sequence TGACTAACGGCT....Ch. 5 - Consider a population containing the following...Ch. 5 - How many redheads live in a village of 250 people,...Ch. 5 - Diagram two processes through which genes can be...Ch. 5 - If a gene gets retroduplicated, how can you...Ch. 5 - How do chromosome inversions happen? What...
Ch. 5 - Diagram the sequence of events that leads to the...Ch. 5 - Discuss factors that might cause mutation rates to...Ch. 5 - Which kind of mutation is most common: lethal,...Ch. 5 - Compare and contrast the evolutionary roles of...Ch. 5 - Suppose a silent mutation occurs in an exon that...Ch. 5 - The amino acid sequences encoded by the red and...Ch. 5 - Chromosome number can evolve by smaller-scale...
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- Would a gain of function mutaion that occurs in the first exon of a gene with twelve exons more likely be missense or nonsense? Briefly explain your choice. List one disease that we studied in class that is due to a gain of function.arrow_forwardHow might a point mutation in DNA affect the phenotype. How the genome is expressed in the organism? (Please explain this at the molecular level).arrow_forwardAll the cells of one organism share the same genome. However, during development, some cells develop into skin cells while others develop into muscle cells. Briefly explain how the same genetic instructions can result in two different cell types in the same organism.arrow_forward
- Defend or attack this statement: “All eukaryotic promoters have TATA boxes.”arrow_forwardA molecular geneticist hopes to find a gene in human liver cells that codes for an important blood-clotting. He knows that the nucleotide sequence of a small part of the gene is GTGGACTGACA. Briefly explain how to obtain the desired gene.arrow_forwardIf the sequence was mutated from CACGTAAAG to become CACCGTAAAG; what type of mutation has occurred? Describe its influence on the gene productarrow_forward
- A molecular geneticist hopes to find a gene gene in human liver cells that codes for an important blood clotting protein. He knows that the nucleotides sequence of a small part of the gene is GTGGACTGACA. briefly explain how to obtain the desired genearrow_forwardA person treated successfully by gene therapy will still have a defective copy of the gene. Explain why.arrow_forwardConsider a single base insertion mutation between the 3rd and 4th codons in a natural gene that encodes a protein 100 amino acids long. Is it more likely that the protein produced by this mutant allele will be shorter or longer than 100 amino acids long?arrow_forward
- Suppose we take tissue samples from the kidney and the liver of a healthy individual. If we compare the genetic sequences in these tissues, what do we expect to see? If we compare the transcription products of these cells, what do we expect to see? Justify your answers.arrow_forwardA geneticist discovers that two different proteins are encoded by the same gene. One protein has 56 amino acids, and the other has 82 amino acids. Provide a possible explanation for how the same gene can encode both of these proteins.arrow_forwardYou have the following DNA coding sequence of a wild-type allele: 5’-ATG TTC CAG CTA GAT GAT ATG CTG GTA ATT GGG GAA CGC GCG CGG TAA-3’ For each of the following mutations: A. State whether the mutation is missense, nonsense, frameshift, or silent. B. Write the codon change that occurs for the missense, nonsense, and silent mutations (ex. GAA -- GAT). C. For frameshift mutations, write out the entire mutant sequence with each codon clearly indicated (if the frameshift creates a new stop codon, end the sequence at the new stop). Using the wild type DNA sequence above as a guide : Write the amino acid sequence of the mutants. Mutant 1: transition at nucleotide 23 Mutant 2: T --> G transversion at nucleotide 29 Mutant 3: an insertion of “A” after nucleotide 14 Mutant 4: transition at nucleotide 7 Mutant 5: An insertion of GG after nucleotide 40 Mutant 6: transition at nucleotide 15 Mutant 7: a deletion of nucleotide 25arrow_forward
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