hange the peptide to Met Asp Asn Gly Leu Gly ? Use the codon numbers to help describe where the mutation is located . What mutation(s) would eliminate peptide translation? Use the codon numbers to help de
Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
codon: 1 2 3 4 5 6 7
sequence: TAC ATG GAC AAT GAT TAG GGG
1. What is the sequence of the peptide that would result following translation with a ribosome?
Write your answer like this Met Ala Gly......
2. What mutation(s) would change the peptide to Met Asp Asn Gly Leu Gly ?
Use the codon numbers to help describe where the mutation is located
. What mutation(s) would eliminate peptide translation?
Use the codon numbers to help describe where the mutation is located
![Using this sequence with the codons numbered and the codon table, answer the following questions:
codon:
1
2
4
5 6
7
sequence: TÁC ATG GÁC AAT GAT TAG GGG
Second Letter
U
A
G
Phe UCU
UCC
UCA
UCG
UUU
UGU
UGC
UGA Stop
Trp
UAU
UAC
Тyr
Cys u
Ser
UUC
UUA
UUG
UAA
UAG
Stop
Stop
Leu
UGG
CAU
CAC
His
CUU
C CUC
CUA
CUG
CCU
Leu | ccc
ССА
CCG
CGU
U
Pro
CGC
CGA
Arg
A
3rd
G
САА
Gln
1st
CAG
CGG
letter
letter
|
Ser u
AUU
A AUC
ACU
ACC
AAU
AAC
AGU
AGC
AGA
Asn
lle
Thr
AUA
ACA
AAA
Lys
Arg
AUG
Met ACG
AAG
AGG
GUU
G GUC
GUA
GUG
GCU
GCC
GCA
GAU
GAC
GGU
GGC
Asp
Val
Ala
Gly
GAA
GAG
GGA
GGG
Glu
GCG
1. What is the sequence of the peptide that would result following translation with a ribosome?
Write your answer like this Met Ala Gly..
2. What mutation(s) would change the peptide to Met Asp Asn Gly Leu Gly ? 2
Use the codon numbers to help describe where the mutation is
located
3. What mutation(s) would change the original peptide to Met lle Arg? [answer3] Use the codon numbers to help describe where the mutation is located
4. What mutation(s) would change the original peptide to Met Glu Gln? Met - Glu - Gln -In c Use the codon numbers to help describe where the mutation is located
5. What mutation(s) would eliminate peptide translation?
Use the codon numbers to help describe where the mutation is located
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