Using the given data, whether inhibition by 2 m urea is competitive or noncompetitive is to be determined. Concept introduction: Competitive inhibition occurs when a substance that is not the substrate of the enzyme under normal condition can also bind to the enzyme’s active site. This results in direct competition with the substrate for the active site. Noncompetitive inhibition occurs when an inhibitor binds to a site present on the enzyme that is distinct from the active site which causes an alteration in the shape of the active site, making it unavailable for the substrate.

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Chapter 22, Problem 26P

Interpretation Introduction

Interpretation:

Using the given data, whether inhibition by 2 m urea is competitive or noncompetitive is to be determined.

Concept introduction:

Competitive inhibition occurs when a substance that is not the substrate of the enzyme under normal condition can also bind to the enzyme’s active site. This results in direct competition with the substrate for the active site. Noncompetitive inhibition occurs when an inhibitor binds to a site present on the enzyme that is distinct from the active site which causes an alteration in the shape of the active site, making it unavailable for the substrate.

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