Concept explainers
(a)
Interpretation:
The products obtained from the given crossed Claisen condensation reaction and the combinations which are poor choices for this reaction are to be stated.
Concept introduction:
In crossed claisen condensation, an ester without the alpha hydrogen adds to a solution of the alkoxide base. The reaction of ester with alpha hydrogens to this solution is slow where it forms enolate and condenses. In this reaction, the electrophilic component is ester without alpha hydrogens.
(b)
Interpretation:
The products obtained from the given crossed Claisen condensation reaction and the combinations which are poor choices for this reaction are to be stated.
Concept introduction:
In crossed claisen condensation, an ester without the alpha hydrogen adds to a solution of the alkoxide base. The reaction of ester with alpha hydrogens to this solution is slow where it forms enolate and condenses. In this reaction, the electrophilic component is ester without alpha hydrogens.
(c)
Interpretation:
The products obtained from the given crossed Claisen condensation reaction and the combinations which are poor choices for this reaction are to be stated.
Concept introduction:
In crossed claisen condensation, an ester without the alpha hydrogen adds to a solution of the alkoxide base. The reaction of ester with alpha hydrogens to this solution is slow where it forms enolate and condenses. In this reaction, the electrophilic component is ester without alpha hydrogens.
(d)
Interpretation:
The products obtained from the given crossed Claisen condensation reaction and the combinations which are poor choices for this reaction are to be stated.
Concept introduction:
In crossed claisen condensation, an ester without the alpha hydrogen adds to a solution of the alkoxide base. The reaction of ester with alpha hydrogens to this solution is slow where it forms enolate and condenses. In this reaction, the electrophilic component is ester without alpha hydrogens.
Want to see the full answer?
Check out a sample textbook solutionChapter 22 Solutions
Organic Chemistry (9th Edition)
- What explains why many aldehydes and ketones can undergo self-condensation reactions in basic conditions? The alpha carbon can lose a proton and act like a nucleophile and the carbonyl carbon is an electrophile. The alpha carbon can gain a proton and act like an electrophile and the carbonyl carbon is a nucleophile. The oxygen of the carbonyl group can attack the carbon of the carbonyl group. Only esters can undergo self-condensation reactions.arrow_forwardChoose the most correct set of reagents for the following reaction.arrow_forwardDraw the enol tautomers for each of the following compounds. For compounds that have more than one enol tautomer, indicate the one that is more stable.arrow_forward
- What explains why many aldehydes and ketones can undergo self- condensation reactions in basic conditions? The alpha carbon can lose a proton and act like a nucleophile and the carbonyl carbon a an electrophile O The alpha carbon can gain a proton and act like an electrophile and the carbonyl carbon is a nucleophile O The oxygen of the carbonyl group can attack the carbon of the carbonyl group Only esters can undergo self-condensation reactionsarrow_forwardChoose the best reagents to complete the following reactions.arrow_forwardRank the following esters in order of decreasing reactivity in the first slow step of a nucleophilic acyl substitution reaction (formation of the tetrahedral intermediate):Rank the same esters in order of decreasing reactivity in the second slow step of a nucleophilic acyl substitution reaction (collapse of the tetrahedral intermediate).arrow_forward
- Draw the major organic product of the following reaction. O OH NH2 X DCCarrow_forwardThe major product that will form during the nitration of benzoic acid is? OA H₂N OR O-N ос OD. NO₂ COOH COOH COOR NH₂ COOH OZN H-N COOH COOHarrow_forwardIdentify the best reagents to complete the following reaction. Options are included.arrow_forward
- Rank the following esters from most reactive to least reactive in the first slow step of a nucleophilic acyl substitution reaction (formation of the tetrahedral intermediate): Rank the same esters from most reactive to least reactive in the second slow step of a nucleophilic acyl substitution reaction (collapse of the tetrahedral intermediate).arrow_forwardWrite out the synthesis for each of the following reactions. Show the product and reagents for each step in each synthesis.?arrow_forwardWhich of the following synthetic routes will convert 3-methyl-2-butanol into 3-methyl-1-butanol?arrow_forward
- Organic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage LearningOrganic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning